Recruiting

Observational Study

Sponsor:

Autoimmune Neurology Alliance

Code:

NCT07761026

Conditions

Myasthenia Gravis (MG)

Myasthenia Gravis, Generalized

Myasthenia Gravis, Ocular

Myasthenia Gravis Crisis

Myasthenia Gravis Associated With Thymoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of the AXIS Autoimmune Neurology Registry is to learn about the experiences of adults living with autoimmune neurological disorders, starting with myasthenia gravis (MG), over time.

The main questions the registry aims to answer are:

  • How do symptoms, daily functioning, and quality of life change over time?
  • What treatments do participants use, and how are these treatments related to their symptoms and health?
  • What challenges do participants experience with treatment, including side effects, treatment burden, missed doses, and access to care?

Participants will:

  • Join the registry and complete an enrollment survey (online or through a mobile app)
  • Complete a brief online survey about their MG approximately once a month
  • Provide information that can help confirm their MG diagnosis
  • Optionally, share their medical records with the research team

This is an observational study. The registry will not assign treatments or ask participants to change their medical care. Information collected through the registry may help researchers better understand MG and improve future research and care.

Conditions

Myasthenia Gravis (MG)

Myasthenia Gravis, Generalized

Myasthenia Gravis, Ocular

Myasthenia Gravis Crisis

Myasthenia Gravis Associated With Thymoma

Study ID

NCT07761026

Start date

Mar 19, 2026

Status verified date

Aug, 2026

Completion date

Mar, 2036

Anticipated

Primary completion date

Mar, 2036

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Physician-confirmed diagnosis of myasthenia gravis (MG)
  • Willing and legally able to provide consent
  • Lives in the United States

Exclusion Criteria:

  • Unwilling or unable to provide consent or comprehend and complete questionnaires
  • Cognitively impaired adults/unable to comprehend or understand the consent or overall study information

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

Myasthenia Gravis (MG)

Adults with confirmed diagnosis of MG

Primary outcome measure

  • MG-ADL [ Time Frame: through study completion, up to 10 years ]

Central Contacts and Locations

Central contacts

President, Board of Directors, Autoimmune Neurology Alliance

info@ainalliance.org

Locations

Alira Health - Virtual/Remote Site - Can Be Completed 100% Online - All US Residents Accepted

Recruiting

Framingham, Massachusetts, United States, 01702

Contacts

AXIS Patient Registry Team - US

765-632-2517support@axispatientregistry.com

President, Board of Directors, Autoimmune Neurology Alliance

info@ainalliance.org

Principal Investigator:

Jared R Adams, MD, PhD

More Information

Sponsor

Autoimmune Neurology Alliance

Last update posted

Aug 17, 2026

Last verified

Aug, 2026

Keywords

  • myasthenia gravis
  • autoimmune diseases of the nervous system
  • neuromuscular junction diseases
  • patient registries
  • natural history
  • longitudinal studies
  • observational study
  • patient-reported outcome measures
  • quality of life
  • activities of daily living
  • treatment patterns
  • medication adherence
  • treatment burden
  • healthcare utilization
  • disease progression
  • real-world data

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Autoimmune Neurology Alliance on 2026-08-17.