Recruiting

Skin Hydration

Sponsor:

IAS Skin Care

Code:

NCT07764809

Conditions

Skin Diseases

Photoaging

Skin Hydration

Eligibility Criteria

Sex: Female

Age: 25 - 65

Healthy Volunteers: Accepted

Interventions

BT-Analyze bioimpedance skin hydration measurement

Study Details

Brief summary:

his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry.

Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.

Conditions

Skin Diseases

Photoaging

Skin Hydration

Study ID

NCT07764809

Start date

Oct 5, 2026

Status verified date

Oct, 2026

Completion date

Mar 1, 2027

Anticipated

Primary completion date

Mar 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 25 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Female sex, aged 25 to 65 years (inclusive)
  • Valid driver's license and active driving for a minimum of 3 years
  • Driving frequency of at least 3 days per week on average
  • Florida residency for a minimum of 2 years prior to enrollment
  • Ability to provide written informed consent in English or Russian

Exclusion Criteria:

  • Window tinting on the driver-side window of the participant's primary vehicle
  • Regular sunscreen application specifically to the left side of the face before driving (more than half of driving occasions in the past month)
  • Active skin disease on the face at time of assessment
  • Injectable cosmetic procedures (Botox or fillers) in the past 6 months
  • Laser resurfacing or chemical peel in the past 3 months
  • Inability to refrain from facial cosmetics for at least 2 hours prior to the visit

Study Design

Enrollment

80 participants

Anticipated

Interventions and Outcome Measures

Arms

Female Florida Drivers

Female drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window.

Interventions

BT-Analyze bioimpedance skin hydration measurement

Non-invasive skin hydration measurement at three facial zones (right cheek, left cheek, forehead) using the BT-Analyze bioimpedance device. Three measurements per zone. Single visit.

Primary outcome measure

  • Hydration Asymmetry Index (HAI) [ Time Frame: Single visit (Day 1) ]

Central Contacts and Locations

Central contacts

Olga IAS, M.Sc

689-249-26-77ias.skincare1@gmail.com

Locations

IAS Skin Care

Recruiting

Orlando, Florida, United States, 32835

Contacts

Olga IAS, M.Sc

689-249-2677ias.skincare1@gmail.com

More Information

Sponsor

IAS Skin Care

Last update posted

Oct 13, 2026

Last verified

Oct, 2026

Keywords

  • skin hydration
  • UVA exposure
  • driving
  • photoaging
  • bioimpedance
  • facial asymmetry
  • Florida
  • BT-Analyze

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-14. This information was provided to ClinicalTrials.gov by IAS Skin Care on 2026-10-13. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.