Recruiting

Eggshell Membrane & Curcumin

Sponsor:

ESM Technologies, LLC

Code:

NCT07766720

Conditions

Exercise-induced Muscle Soreness

Exercise-induced Joint Pain

Exercise-induced Joint Stiffness

Exercise-induced Cartilage Turnover

Eligibility Criteria

Sex: Male

Age: 18 - 40

Healthy Volunteers: Accepted

Interventions

NEM® brand eggshell membrane powder

curQ+® brand highly absorbable curcumin

EM Placebo

Curc Placebo

NEM® plus curQ+® combination

Study Details

Brief summary:

Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery. This proof-of-concept study will examine how ingestion of specially formulated versions of these nutrients affects recovery from intense exercise.

Conditions

Exercise-induced Muscle Soreness

Exercise-induced Joint Pain

Exercise-induced Joint Stiffness

Exercise-induced Cartilage Turnover

Study ID

NCT07766720

Start date

Feb 1, 2026

Status verified date

Aug, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Oct 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18 - 40

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age 18 to 40 at the time of consent.
  • Healthy and recreationally active.
  • Ability to comply with study procedures.
  • Agree to refrain from alcohol intake and use of non-steroidal anti-inflammatory (NSAIDS), aspirin, and other over-the-counter pain medications for 48 hours prior to and after completion of each testing session.

Exclusion Criteria:

  • No recent history of exercise training
  • An orthopedic limitation that would prevent the ability to perform the exercise intervention.
  • Participants who currently smoke cigarettes.
  • Known allergies to eggs, sulfur, or curcumin.

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Active, EM

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule.

experimental: Active, curc

2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

placebo comparator: Placebo

500 mg/day of psyllium husk fiber powder in a single #0 capsule PLUS 2,860 mg/day of coconut oil/polysorbate blend in a single 10 Oval softgel.

experimental: Active, EM+Curc

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule PLUS 2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

Interventions

NEM® brand eggshell membrane powder

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule.

curQ+® brand highly absorbable curcumin

2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

EM Placebo

500 mg/day of psyllium husk fiber powder in a single #0 capsule.

Curc Placebo

2,860 mg/day of coconut oil/polysorbate blend in a single 10 Oval softgel.

NEM® plus curQ+® combination

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule PLUS 2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

Primary outcome measure

  • VAS Muscle Soreness Rating [ Time Frame: 2 weeks ]

Central Contacts and Locations

Central contacts

Richard B. Kreider, Ph.D.

(979) 458-1498rbkreider@tamu.edu

Christopher Rasmussen, M.S.

(979) 458-1498crasmussen@tamu.edu

Locations

Exercise & Sport Nutrition Lab - Texas A&M University

Recruiting

College Station, Texas, United States, 77843

Contacts

Richard B. Kreider, Ph.D.

(979) 458-1498rbkreider@tamu.edu

Christopher Rasmussen, M.S.

(979) 458-1498crasmussen@tamu.edu

Principal Investigator:

Richard B. Kreider, Ph.D.

More Information

Sponsor

ESM Technologies, LLC

Last update posted

Aug 14, 2026

Last verified

Aug, 2026

Keywords

  • intense exercise
  • NEM
  • curQ+
  • eggshell membrane
  • curcumin

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-07. This information was provided to ClinicalTrials.gov by ESM Technologies, LLC on 2026-08-14. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.