Recruiting

Observational Study

Sponsor:

Translational Genomics Research Institute

Code:

NCT07767227

Conditions

Pancreatic Cyst

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of this study is to collect biospecimens (blood and cystic fluid) and data from participants who have a pancreatic cyst that requires surgical resection. The blood and fluid samples will be analyzed for research into DNA, RNA, and proteins.

Conditions

Pancreatic Cyst

Study ID

NCT07767227

Start date

Feb 3, 2025

Status verified date

Jul, 2026

Completion date

Mar, 2028

Anticipated

Primary completion date

Dec, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Voluntarily agree to participate by giving written informed consent prior to any study-specific procedures.
  • Subject at least 18 years of age and able to provide consent. Subject is willing and able to comply with requirements of the protocol.
  • Radiologically documented cyst of the pancreas for which surgical removal is clinically indicated.
  • Patient will be undergoing a surgical resection of their pancreatic cystic neoplasm.

Exclusion Criteria:

  • Patient who is pregnant at the time of study enrollment and sample collection.
  • Patient will not be undergoing clinically indicated surgery for a pancreatic cystic neoplasm.
  • Patient is unwilling or unable to provide informed consent or comply with study procedures.

Study Design

Enrollment

30 participants

Anticipated

Interventions and Outcome Measures

Arms

Pancreatic cyst

Patients who are or will be scheduled for surgical resection of their worrisome pancreatic cyst as part of their clinically indicated care.

Primary outcome measure

  • Characterize the miRNA and protein signatures in exosomes derived from blood and cyst fluids in patients with worrisome cystic pancreatic tumors [ Time Frame: At enrollment ]

Central Contacts and Locations

Central contacts

Michael Demeure, MD

949-764-4577clinicalresearch@hoag.org

Locations

Hoag Family Cancer Institute

Recruiting

Newport Beach, California, United States, 92663

Contacts

Michael Demeure, MD

949-764-4577clinicalresearch@hoag.org

Piedmont HealthCare

Recruiting

Atlanta, Georgia, United States, 30309

Contacts

Andrew Page, MD

(404) 605-7100andrew.page@piedmont.org

More Information

Sponsor

Translational Genomics Research Institute

Last update posted

Aug 17, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Translational Genomics Research Institute on 2026-08-17.