Recruiting
Phase 1

MT-201 with Infliximab

Sponsor:

Mirador Therapeutics, Inc.

Code:

NCT07776782

Conditions

Healthy Volunteer

Eligibility Criteria

Sex: All

Age: 19 - 55

Healthy Volunteers: Accepted

Interventions

MT-201

Study Details

Brief summary:

A Phase 1, Open-Label, Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of MT-201 Administered with Concomitant Infliximab in Healthy Participants

Conditions

Healthy Volunteer

Study ID

NCT07776782

Start date

Jul 16, 2026

Status verified date

Aug, 2026

Completion date

Nov 12, 2026

Anticipated

Primary completion date

Nov 12, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19 - 55

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Male or female (of non-childbearing potential only) between 19 and 55 years of age inclusive, at the time of signing informed consent.
2. Females must be of non-childbearing potential and must have undergone sterilization procedures, and have official documentation, at least 6 months prior to the first dose.
3. Male subjects must use highly effective forms of contraception during sexual intercourse with female partners of childbearing potential.
4. Good general health.
5. Able to provide written informed consent and understand and comply with the requirements of the study.

Exclusion Criteria:

1. History or presence of any clinically significant organ system disease.
2. Abnormal laboratory assessments, physical exam of ECG outside the normal range that is judged by the Investigator to be clinically significant.
3. History of alcohol or drug abuse within the past 24 months.
4. Current use or history of regular tobacco, or nicotine-containing products within 3 months prior to screening.
5. Administration of any prescription drug within 21 days or 5 half-lives (whichever is longer) of study drug administration; or over-the-counter drug within 7 days or 5 half-lives (whichever is longer) of study drug administration.
6. Administration or use of any investigational drug or device within 30 days preceding the first does of study drug administration.
7. Blood donation within 60 days prior to dosing or plasma donation within 14 days prior to dosing.
8. Sensitivity to any of the study drugs, or components thereof, or drug or other allergy that in the opinion of the Investigator or Sponsor Medical Monitor, contraindicates participation in the study.

Study Design

Enrollment

25 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Single Dose of MT-201 and Concomitant Infliximab

To evaluate the safety and tolerability of single doses of MT-201 and Concomitant Infliximab

Interventions

MT-201

MT-201 and Infliximab

Primary outcome measure

  • Number of Participants with non-SAEs and SAES [ Time Frame: Up to 8 weeks post dose ]

Central Contacts and Locations

Central contacts

Locations

Mirador Clinical Department

Recruiting

San Diego, California, United States, 92121

Contacts

More Information

Sponsor

Mirador Therapeutics, Inc.

Last update posted

Aug 21, 2026

Last verified

Aug, 2026

Keywords

  • Phase 1
  • MT-201

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mirador Therapeutics, Inc. on 2026-08-21.