Recruiting

TRTME

Sponsor:

T. John Winhusen, PhD

Code:

NCT07780097

Conditions

Opioid Use Disorder

Opioid Use Disorder, Moderate

Opioid Use Disorder, Severe

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

TRTME

Study Details

Brief summary:

The primary objective of this study is to evaluate the ability of TRTME to increase initiation of MOUD outpatient treatment and MOUD knowledge in hospitalized patients with OUD deemed to be good candidates for MOUD by the UCMC Addiction Consult Team (ACT). The secondary objective is to evaluate the ability of TRTME to decrease stigma and increase drug self-efficacy.

Conditions

Opioid Use Disorder

Opioid Use Disorder, Moderate

Opioid Use Disorder, Severe

Study ID

NCT07780097

Start date

Aug 12, 2026

Status verified date

Aug, 2026

Completion date

Feb 28, 2027

Anticipated

Primary completion date

Feb 28, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. 18 years of age or older;
2. A good candidate for methadone or buprenorphine treatment according to a member of the UCMC Addiction Consult Team

Exclusion Criteria:

1. Have a current planned discharge to a nursing facility
2. be currently in jail, prison, or any inpatient overnight facility as required by court of law or have pending legal action with high probability of incarceration or court-mandated inpatient treatment
3. Unable to demonstrate adequate understanding of study procedures during the consent process

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

no intervention: Control

Control participants will be offered two SAMHSA handouts: 1) "Opioid Overdose Prevention Toolkit: Safety Advice for Patients and Family Members"; and 2) "Medication-Assisted Treatment for Opioid Addiction: Facts for Families and Friends". These handouts can be offered as physical copies or electronically.

experimental: TRTME

TRTME participants will be offered a 15-minute intervention in which a trained research staff member reviews personal feedback reports with the recipient to provide information on: 1) the items missed on the knowledge assessment; and 2) their personal overdose risk factors. TRTME participants will also have the opportunity to view short videos from patients talking about their experiences with methadone or buprenorphine treatment.

Interventions

TRTME

The TRTME intervention includes three elements that have all been previously studied by our research team: 1) brief, personally-tailored education to correct inaccurate, common misconceptions about MOUD and to address knowledge gaps about opioid-overdose; 2) with personally-tailored feedback on the individual's risk factors for experiencing an opioid-overdose; and 3) review of MOUD testimonial videos.

Primary outcome measure

  • Outpatient MOUD initiation [ Time Frame: 30 days ]

Central Contacts and Locations

Central contacts

Lindsay Bybee, MS

5135858282saskowld@uc.edu

Ben Kropp Kropp, MSLS

5135858287kroppbn@ucmail.uc.edu

Locations

University of Cincinnati Addiction Sciences Division

Recruiting

Cincinnati, Ohio, United States, 45229

More Information

Sponsor

T. John Winhusen, PhD

Last update posted

Aug 21, 2026

Last verified

Aug, 2026

Keywords

  • opioid
  • Opioid Use Disorder
  • MOUD
  • buprenorphine
  • methadone

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by T. John Winhusen, PhD on 2026-08-21.