Recruiting

UNITY Dx vs. Anterion

Sponsor:

Alcon Research

Code:

NCT07782619

Conditions

Anterior Segment of Eye

Axial Length

Biometrics Measurement

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Interventions

UNITY DX

ANTERION

Study Details

Brief summary:

The purpose of this study is to compare the measurements obtained with two different biometers, UNITY Dx and Anterion. In eye care, a biometer is a device that uses laser technology to take highly precise measurements of the eye's internal structures. It is most frequently used to help determine the exact power of the intraocular lens (IOL) needed before cataract removal.

Conditions

Anterior Segment of Eye

Axial Length

Biometrics Measurement

Study ID

NCT07782619

Start date

Aug 17, 2026

Status verified date

Aug, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Have healthy, clear corneas for the normal cohort;
  • Have documented keratoconus for the keratoconus cohort;
  • Have reported use of daily contact lens use for the contact lens cohort;
  • Have documented dry eye, consisting of signs and symptoms for the dry eye cohort;
  • Has had previous keratorefractive surgery for the post-refractive surgery cohort;
  • Able to comprehend and sign the informed consent form.

Exclusion Criteria:

  • Active ocular infection or inflammation;
  • Unable to fixate due to nystagmus or other eye movement abnormality (e.g., significant strabismus);
  • Any ocular disease and/or condition that, in the investigator's clinical judgment, may put the subject at significant risk, may compromise study result or may interfere significantly with the subject's participation in the study.

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Arms

Normal Corneas

This cohort will enroll subjects with normal corneas.

Keratoconus

This cohort will enroll subjects with keratoconus.

Prior Corneal Laser Vision Correction

This cohort will enroll subjects with prior corneal laser vision correction.

Current and Habitual Contact Lens Wear

This cohort will enroll subjects with current and habitual contact lens wear.

Dry Eye

This cohort will enroll subjects with dry eye.

Interventions

UNITY DX

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and their optical properties

ANTERION

Commercially available non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and their optical properties

Primary outcome measure

  • Regression-Based Axial Length (R-AL) [ Time Frame: Day 1 ]

Central Contacts and Locations

Central contacts

Alcon Call Center

1-888-451-3937alcon.medinfo@alcon.com

Locations

The Eye Institute of Utah

Recruiting

Salt Lake City, Utah, United States, 84107

More Information

Sponsor

Alcon Research

Last update posted

Sep 2, 2026

Last verified

Aug, 2026

Keywords

  • Biometer

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Alcon Research on 2026-09-02.