Recruiting

Gallbladder Ultrasound

Sponsor:

WellSpan Health

Code:

NCT07792200

Conditions

Cholecystitis, Acute

Biliary Diseases

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Repeat biliary point of care ultrasound

Study Details

Brief summary:

The goal of this interventional, prospective study is to determine the clinical utility of a repeat point-of-care ultrasound of the gallbladder in adult emergency department patients with abdominal pain for which initial imaging is not diagnostic. The main question it aims to answer is: Does a repeat ultrasound improve early identification of gallbladder inflammation?

Participants will undergo a repeat ultrasound of the gallbladder while still in the emergency department and will be followed up to determine subsequent diagnoses, disposition, consultations and other clinical information.

Conditions

Cholecystitis, Acute

Biliary Diseases

Study ID

NCT07792200

Start date

Jun 1, 2026

Status verified date

Jun, 2026

Completion date

Dec 31, 2028

Anticipated

Primary completion date

Jul 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ≥ 18 years of age
  • Presenting to the emergency department with abdominal pain with clinical concern for possible acute cholecystitis
  • Initial biliary US interpreted as normal, equivocal or negative for acute cholecystitis
  • 2-6 hours since initial biliary ultrasound with ongoing symptoms
  • General surgery consult placed or additional non-ultrasound advanced imaging ordered
  • Fluency in English or Spanish

Exclusion Criteria:

  • < 18 years of age
  • > 6 hours since initial biliary US
  • Asymptomatic/resolved symptoms or pending discharge from the emergency department
  • Initial ultrasound positive for acute cholecystitis or other findings to explain presenting symptoms
  • Baseline ascites
  • Prior cholecystectomy
  • Unable or unwilling to provide consent
  • Presenting to a facility other than study site emergency department
  • Transferred patients from outside facilities

Study Design

Enrollment

90 participants

Anticipated

Intervention Model

Single group

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

experimental: Repeat biliary point-of-care ultrasound

Repeat point-of-care ultrasound to be performed 2-6 hours from time of initial ultrasound imaging study

Interventions

Repeat biliary point of care ultrasound

Repeat biliary point of care ultrasound to be performed 2-6 hours following initial ultrasound imaging study

Primary outcome measure

  • Number of patients diagnosed with acute cholecystitis [ Time Frame: Within 30 days of enrollment ]

Central Contacts and Locations

Central contacts

Brent Becker Principal Investigator, MD

717-851-4819bbecker2@wellspan.org

Kristen Wilhelm Research Coordinator, MS

717-812-5075kwilhelm6@wellspan.org

Locations

WellSpan Health York Hospital

Recruiting

York, Pennsylvania, United States, 17403

Contacts

Kristen Wilhelm, MS

717-812-5075kwilhelm6@wellspan.org

Brent Becker, MD

717-851-4819bbecker2@wellspan.org

More Information

Sponsor

WellSpan Health

Last update posted

Aug 28, 2026

Last verified

Jun, 2026

Keywords

  • Acute Cholecystitis
  • Point of Care Ultrasound
  • Emergency Department
  • Biliary Disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by WellSpan Health on 2026-08-28.