Recruiting

Juvéderm & OnabotulinumtoxinA

Sponsor:

AbbVie

Code:

NCT07794891

Conditions

Jawline and Neck Appearance

Eligibility Criteria

Sex: All

Age: 22 - 65

Healthy Volunteers: Not accepted

Interventions

OnabotulinumtoxinA

SKINVIVE

VOLUX

VOLUMA

Study Details

Brief summary:

The goal of this study is to evaluate overall participant satisfaction with the jawline and neck.

Participants will receive select Juvéderm products and onabotulinumtoxinA in the jaw area and neck per eligibility criteria.

The study will measure changes in psychological function, satisfaction with lower face and jawline and skin appearance. Participants will attend visits during the study at a clinical site. The effects of the treatment will be checked by medical assessments, vital signs, physical examinations, checking for side effects, and completing questionnaires.

Conditions

Jawline and Neck Appearance

Study ID

NCT07794891

Start date

Sep 9, 2026

Status verified date

Oct, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 22 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Moderate or severe transverse neck lines based on investigator's live assessment
  • Moderate or severe loss of jawline definition based on investigator's live assessment.
  • Moderate or severe platysma prominence based on investigator's live assessment.

Exclusion Criteria:

  • History of or current medical condition that may put the subject at increased medical risk with exposure to BOTOX, or any other condition that might interfere with neuromuscular function.
  • History of or current symptoms of dysphagia.
  • History of severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies.
  • History of hypersensitivity or allergy to any botulinum toxin serotype, Streptococcal or gram-positive bacterial proteins, lidocaine, HA products, any other excipients or constituents of the study drug, device, and/or other products in the same class.
  • History of or tendency for keloid formation, hyperpigmentation, or hypertrophic scarring.

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: JUVÉDERM Products Plus OnabotulinumtoxinA

Participants in the study will receive the products in the jaw area, chin, and neck.

Interventions

OnabotulinumtoxinA

Injection

SKINVIVE

Injection

VOLUX

Injection

VOLUMA

Injection

Primary outcome measure

  • Percentage of Participants With Response of Satisfied or Very Satisfied on Appearance of Neck and Lower Face Questionnaire (ANLFQ): Satisfaction Follow-Up [ Time Frame: Day 104 ]

Central Contacts and Locations

Central contacts

ABBVIE CALL CENTER

844-663-3742abbvieclinicaltrials@abbvie.com

Locations

Humphrey & Beleznay Cosmetic Dermatology /ID# 282598

Recruiting

Vancouver, British Columbia, Canada, V5Z 4E1

Sweat Clinics Of Canada /ID# 281845

Recruiting

Toronto, Ontario, Canada, M5R 3N8

More Information

Sponsor

AbbVie

Last update posted

Oct 8, 2026

Last verified

Oct, 2026

Keywords

  • AURA Study
  • Jaw area and Neck Appearance
  • onabotulinumtoxinA
  • JUVÉDERM

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-09. This information was provided to ClinicalTrials.gov by AbbVie on 2026-10-08. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.