Recruiting

MedDiet-SN & MedDiet-WL

Sponsor:

University of Illinois at Chicago

Code:

NCT07798557

Conditions

Obesity & Overweight

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Accepted

Interventions

Social Network Curriculum

Study Details

Brief summary:

Aim 1. Conduct a 6-month (24-session) RCT comparing MedDiet-WL to MedDiet-SN among 268 older adults with obesity (50-79 years, BMI = 30-50 kg/m²). We hypothesize that 1) Participants in MedDiet-SN will show improvements in bodyweight/BMI and body fat compared to MedDiet-WL at post-intervention (6-months), 2) Participants in MedDiet-SN will show improvements in diet (diet quality) and physical activity (step counts) compared to MedDiet-WL at post-intervention (6-months), and 3) Participants in MedDiet-SN will maintain these improvements at 12-months.

Aim 2. Characterize and compare differences in weight management information dissemination by 268 randomized to MedDiet-WL and MedDiet-SN. We hypothesize that MedDiet-SN participants will share information to more network members compared to participants in MedDiet-WL.

Aim 3. Compare MedDiet-SN and MedDiet-WL in 268 network members. We hypothesize that MedDiet-SN network members will show, greater improvements in BMI, body fat, diet, and physical activity than MedDiet-WL network members at 6 months. We will explore how effects may vary by network (e.g., density, relationships), and messaging characteristics (e.g., modality).

Conditions

Obesity & Overweight

Study ID

NCT07798557

Start date

Feb 1, 2026

Status verified date

Aug, 2026

Completion date

Dec 31, 2029

Anticipated

Primary completion date

Jun 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 50-79 yrs old,
  • BMI 30-50
  • Willing to participate in all procedures
  • Understand English
  • Willing to make changes to diet and lifestyle
  • Have access to a phone
  • Plan to reside in the Chicago area for the next 12 months

Exclusion Criteria:

  • Severe ischemic heart disease
  • Severe pulmonary disease
  • Bariatric surgery
  • Cancer treatment within the past 12 months
  • Current adherence to MedDiet based on dietary screening

Study Design

Enrollment

532 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: MD-WL

Mediterranean Diet Weight Loss

active comparator: MD-WL SN

Mediterranean Diet Weight Loss Social Networks

Interventions

Social Network Curriculum

Empowerment to share lifestyle change information within social networks

Primary outcome measure

  • Physical Activity [ Time Frame: 6 months ]
  • Anthropometrics, Body Fat [ Time Frame: 6 months ]
  • Dietary Intake [ Time Frame: 6 months ]
  • Mediterranean Diet adherence [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Lara Blumstein, MA

+1 77304903311lbb@uic.edu

Marian Fitzgibbon, PhD

+1 77304903311lbb@uic.edu

Locations

University of Illinois Chicago

Recruiting

Chicago, Illinois, United States, 60608

Contacts

Marian Fitzgibbon, PhD

3129969028mlf@uic.edu

More Information

Sponsor

University of Illinois at Chicago

Last update posted

Sep 1, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Illinois at Chicago on 2026-09-01.