Recruiting

Yogurt

Sponsor:

Meiji Co., Ltd.

Code:

NCT07799207

Conditions

Immune Function

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

Yogurt drink

Acidified lactic beverage

Study Details

Brief summary:

This study evaluates the effects of daily consumption of a yogurt on immune function and subjective health status in healthy adults in the United States. Participants are randomly assigned to receive either the active yogurt or a placebo once daily for 8 weeks. The study assesses immune function using salivary immunoglobulin A and other immune-related biomarkers. The study also evaluates cold-like symptoms, quality of life, gastrointestinal symptoms, stress, and sleep-related outcomes.

Conditions

Immune Function

Study ID

NCT07799207

Start date

Sep 14, 2026

Status verified date

Sep, 2026

Completion date

Jun 28, 2027

Anticipated

Primary completion date

Jun 28, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Be able to give written informed consent.
  • Be between 18-65 years, inclusive.
  • Be in general good health, as determined by the in investigator.
  • Willing to consume study product daily for the duration of the study.
  • Has a body mass index (BMI) ≤39.9 kg/m2
  • Willing to refrain from consuming alcohol for the 24 hours prior to each study visit.
  • Willing to maintain current lifestyle habits, including dietary and caffeine and alcohol intake, for the duration of the study.

Exclusion Criteria:

  • Participants who are pregnant or wish to become pregnant during the study or who are lactating and/or currently breastfeeding.
  • Participants currently of biological childbearing potential, but not using a continuous effective method of contraception.
  • Has a history of drug and/or alcohol abuse at the time of enrolment.
  • Drinks more than nationally recommended units of alcohol per day/week.
  • Has milk allergy or other food allergies or other issues with foods that would preclude intake of the SP.
  • Has an excessive smoking habit.
  • Has any significant acute or chronic coexisting health conditions that would prevent them from fulfilling the study requirements, put the participant at risk or would confound the interpretation of the study results as judged by the investigator on the basis of medical history and laboratory test results.
  • Dental or intraoral treatment.
  • Visited a hospital or clinic for allergic rhinitis (pollinosis) within the past year or those who plan to take prescription drugs to treat or prevent allergic rhinitis during the study period.
  • Current or recent (in the past 4 weeks) use of a medication that the investigator believes would interfere with the objectives of the study or pose a safety risk or confound the interpretation of the study results.
  • Current or recent (in the past 4-weeks) use of prohibited nutritional or non-nutritional dietary supplements that the investigator believes would interfere with the objectives of the study or pose a safety risk or confound the interpretation of the study results.
  • Current or recent (in the past 2 weeks) use of yogurt (other than the study product)
  • Participants who have donated blood in the previous 8-weeks.
  • Individuals who, in the opinion of the investigator, are considered to be poor attendees or unlikely for any reason to be able to comply with the study.
  • Participants may not be participating in other clinical studies. If the participant has previously taken part in an experimental study, the Investigator must ensure sufficient time has elapsed before entry to this study to ensure the integrity of the results.

Study Design

Enrollment

118 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Active study product

Participants receive 120 g of the yogurt drink once daily for 8 weeks.

placebo comparator: Placebo study product

Participants receive 120 g of the acidified lactic beverage once daily for 8 weeks.

Interventions

Yogurt drink

Participants receive 120 g of the yogurt drink once daily for 8 weeks.

Acidified lactic beverage

Participants receive 120 g of the acidified lactic beverage once daily for 8 weeks.

Primary outcome measure

  • Salivary IgA flow rate [ Time Frame: Baseline (Week 0) and Endpoint (Week 8) ]

Central Contacts and Locations

Locations

Atlantia Clinical Trials

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Stacey Boetto, Principal Investigator

312-535-9440sboetto@atlantiatrials.com

More Information

Sponsor

Meiji Co., Ltd.

Last update posted

Sep 3, 2026

Last verified

Sep, 2026

Keywords

  • Yogurt
  • Immune Function
  • Probiotics
  • Healthy Adults

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Meiji Co., Ltd. on 2026-09-03.