Recruiting

Lifestyle Intervention

Sponsor:

Morehouse School of Medicine

Code:

NCT07808723

Conditions

Weight Reduction

Prediabetes

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Accepted

Interventions

Family Diabetes Prevention

Study Details

Brief summary:

The goal of this clinical trial is to determine whether a family-based lifestyle intervention reduces the risk of type 2 diabetes (T2D) among parents and their children. The intervention will also evaluate how well the program supports healthy lifestyle behaviors and family engagement.

The primary outcome of this study is weight loss in parents.

Researchers will evaluate changes in participants' weight and lifestyle behaviors before the study compared to the end of the study (12 weeks post intervention) and 3 months after participation in the program.

Conditions

Weight Reduction

Prediabetes

Study ID

NCT07808723

Start date

Aug 29, 2026

Status verified date

Sep, 2026

Completion date

Mar, 2028

Anticipated

Primary completion date

Mar, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Parent/guardian must identify as African American or Hispanic
  • Parent/guardian must be 18+ years residing in the same household as the child (i.e., biological or have legal guardianship for child)
  • Parent/guardian must have prediabetes (HbA1c level 5.7-6.4%) or be at risk of developing Type 2 diabetes using CDC's Pre-Diabetes Risk Test
  • Participant is willing to commit to participation in a 12-week, in-person, intervention study
  • No plans to move over the next 9-months
  • Parent/guardian should be ambulatory and able to participate in physical activity
  • Children must be between the ages of 12-17 years old
  • Child should be ambulatory and able to participate in physical activity

Exclusion Criteria:

  • Severe psychological disorders that may prevent/interfere with study -participation
  • Physical impairments that may prevent participation in moderate intensity physical activity
  • Previous diagnosis of diabetes
  • History of congestive heart failure
  • Renal failure
  • Recent (<12 months) cardiovascular events such as myocardial infarction (heart attack) or stroke
  • Taking medications that may affect endpoint analyses
  • Have co-morbid contraindications to physical activity or dietary changes
  • Currently pregnant or planning to become pregnant in the next year
  • Family lives outside of Georgia

Study Design

Enrollment

120 participants

Anticipated

Intervention Model

Single group

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Single arm pre/post study

Interventions

Family Diabetes Prevention

A weekly lifestyle modification program for families with at least one parent at high risk of developing diabetes.

Primary outcome measure

  • Weight Reduction [ Time Frame: From enrollment to the end of intervention at 6 months ]

Central Contacts and Locations

Central contacts

Katrina M Brantley, DrPH

470-670-7840kbrantley@msm.edu

Danielle M Duvernay, MSHI

404-756-1224dduvernay@msm.edu

Locations

Morehouse School of Medicine

Recruiting

Atlanta, Georgia, United States, 30310

Contacts

Katrina M Brantley, DrPH

470-670-7840kbrantley@msm.edu

Danielle M Duvernay, MSHI

404-756-1224dduvernay@msm.edu

Principal Investigator:

Rakale C Quarells, PhD

More Information

Sponsor

Morehouse School of Medicine

Last update posted

Sep 18, 2026

Last verified

Sep, 2026

Keywords

  • Family-based diabetes prevention intervention
  • Cardiovascular Disease Prevention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-24. This information was provided to ClinicalTrials.gov by Morehouse School of Medicine on 2026-09-18. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.