Recruiting

Health Warnings

Sponsor:

University of Oklahoma

Code:

NCT07812545

Conditions

Risk Perceptions

Decision Making

Alcohol

Eligibility Criteria

Sex: Female

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

Health warning statement evaluations (bottles)

Health warning statement evaluations (ads)

Study Details

Brief summary:

Consuming alcohol is a dose-dependent and modifiable risk factor for breast cancer. Although alcohol consumption contributes to an estimated 16% of breast cancer cases, awareness of the link between alcohol and breast cancer risk remains low. Systematically developed and tested health warnings can support population-based approaches and intervention strategies to decrease alcohol consumption and breast cancer risk. For instance, the U.S. Food and Drug Administration can mandate specific warnings through statements (e.g., "WARNING: This product contains nicotine…") and color graphics depicting the negative health consequences of products that can harm public health, such as tobacco and alcohol. However, health warning statements and graphics should be assessed among intended audiences before implementation. Research has outlined principles for effective health warning statements. This project will test different health warning statements about the health effects of alcohol.

Conditions

Risk Perceptions

Decision Making

Alcohol

Study ID

NCT07812545

Start date

Jul 27, 2026

Status verified date

Sep, 2026

Completion date

Sep, 2026

Anticipated

Primary completion date

Sep, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • being between 18 and 65 years of age
  • assigned female at birth
  • self-report having consumed alcohol in the last 30 days for the current drinker groups
  • self-report not having consumed alcohol in the last 30 days for the nondrinker groups
  • live in the US and able to read, speak, and understand English

Study Design

Enrollment

2000 participants

Anticipated

Allocation

Randomized

Intervention Model

Factorial

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Health warning statement evaluations (bottles)

A randomized clinical trial (RCT) cohort of adult participants (18-65) will complete a computer-based survey-experiment during a single study visit (conducted online). They will review a series of hypothetical alcohol products and rate the images.

experimental: Health warning statement evaluations (ads)

A randomized clinical trial (RCT) cohort of adult participants (18-65) will complete a computer-based survey-experiment during a single study visit (conducted online). They will review a series of hypothetical alcohol products and rate the images.

Interventions

Health warning statement evaluations (bottles)

The experiment will use a 2 (health warning statement: single-theme statement vs. composite paragraph) x 2 (pictogram: present vs. absent) x 2 (format: alcohol container vs. alcohol advertisement) between- and within-subjects design. The between-subject groups are 2 (health warning statement: single-theme vs. composite message) x 2 (pictogram: present vs. absent), and the within-subjects factor is the format of warning presentation (2 alcohol containers vs. 2 alcohol advertisements).

Health warning statement evaluations (ads)

The experiment will use a 2 (health warning statement: single-theme statement vs. composite paragraph) x 2 (pictogram: present vs. absent) x 2 (format: alcohol container vs. alcohol advertisement) between- and within-subjects design. The between-subject groups are 2 (health warning statement: single-theme vs. composite message) x 2 (pictogram: present vs. absent), and the within-subjects factor is the format of warning presentation (2 alcohol containers vs. 2 alcohol advertisements).

Primary outcome measure

  • Risk perceptions of alcohol harms (questionnaire self-report) [ Time Frame: Assessed immediately after stimulus exposure. ]
  • Perceived efficacy to prevent alcohol harms (questionnaire self-report) [ Time Frame: Assessed immediately after stimulus exposure. ]
  • Attitudes about alcohol consumption (questionnaire self-report) [ Time Frame: Assessed immediately after stimulus exposure. ]
  • Intentions to quit or reduce drinking alcohol (questionnaire self-report) [ Time Frame: Assessed immediately after stimulus exposure. ]
  • Intentions to seek information about alcohol health effects and cancer screenings (questionnaire self-report) [ Time Frame: Assessed immediately after stimulus exposure. ]

Central Contacts and Locations

Central contacts

Zachary Massey, PhD

(405) 271-6872zachary-massey@ou.edu

Locations

University of Oklahoma Health Campus, Health Promotion Research Center

Recruiting

Oklahoma City, Oklahoma, United States, 73104

Contacts

Zachary Massey, PhD

405-271-6872zachary-massey@ou.edu

More Information

Sponsor

University of Oklahoma

Last update posted

Sep 10, 2026

Last verified

Sep, 2026

Keywords

  • Alcohol health warning statements

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-11. This information was provided to ClinicalTrials.gov by University of Oklahoma on 2026-09-10.