Recruiting

Water Filters

Sponsor:

Virginia Polytechnic Institute and State University

Code:

NCT07818902

Conditions

Diarrhea

Enteric Pathogens

Gastrointestinal Disease

Waterborne Diseases

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Water filter

Study Details

Brief summary:

The goal of this intervention trial is to learn if the use of drinking water filters will result in improved health outcomes for people living in homes with well water and spring water in rural regions of Central Appalachia.

Conditions

Diarrhea

Enteric Pathogens

Gastrointestinal Disease

Waterborne Diseases

Study ID

NCT07818902

Start date

Nov, 2026

Status verified date

Nov, 2026

Completion date

May, 2030

Anticipated

Primary completion date

Mar, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Home is located in a study county in southwest Virginia or northeast Tennessee
  • There is at least one adult (aged 18 or older) who regularly (>6 months per year) resides in the household
  • Household does not have utility-supplied water (and <33% of household members regularly drink bottled water)
  • Reported household income is <80% of the county median income (based on US Department of Housing and Urban Development thresholds by household population)

Exclusion Criteria:

  • None (no exclusion criterion based on gender, race, ethnicity, language, or literacy)

Study Design

Enrollment

1584 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Point-of-use water filter

Households randomized to the treatment group will receive water filters at the beginning of the study.

no intervention: Control

Households randomized to the control group will receive water filters after follow-up data collection is completed.

Interventions

Water filter

Point-of-use multi-stage dispenser water filter with a membrane microfilter and a combined activated carbon and ion exchange filter

Primary outcome measure

  • Acute gastrointestinal illness incidence [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Kelsey Lane Warmbrod, PhD

540-231-1816wlane@vt.edu

Bethesda O'Connell, DrPH

423-439-4816oconnell@etsu.edu

Locations

Virginia Tech

Recruiting

Blacksburg, Virginia, United States, 24060

Contacts

Project Manager

540-231-8814RWELLstudy@vt.edu

More Information

Sponsor

Virginia Polytechnic Institute and State University

Last update posted

Nov 9, 2026

Last verified

Nov, 2026

Keywords

  • Acute Gastrointestinal Illness
  • Central Appalachia
  • Cluster Randomized Controlled Trial
  • Diarrhea
  • Drinking Water Contamination
  • Enteric Pathogens
  • Intervention Trial
  • Point-of-Use Water Treatment
  • Rural Health
  • Spring Water
  • Water Filtration
  • Waterborne Diseases
  • Well Water

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-10. This information was provided to ClinicalTrials.gov by Virginia Polytechnic Institute and State University on 2026-11-09. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.