Recruiting

Myoelectric Prosthetics

Sponsor:

Liberating Technologies, Inc.

Code:

NCT07850544

Conditions

Prosthesis User

Prosthesis

Prosthetic

Upper Limb Amputation

Upper Limb Amputation Below Elbow

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Condition A: Electrode Configuration

Condition B: Electrode Configuration

Condition C: Electrode Configuration

Condition D: Electrode Configuration

Study Details

Brief summary:

This study is focused on optimizing methods for controlling upper-limb myoelectric prosthetic arms. If you are enrolled in this study you would be expected to visit one of the research sites for approximately 5 in-lab visits lasting about 4 hours. These visits are expected to happen within a 5-week period but may take longer depending on scheduling availability. During these visits you will be completing basic tasks similar to your everyday actions using a prosthetic arm that is provided for you.

Conditions

Prosthesis User

Prosthesis

Prosthetic

Upper Limb Amputation

Upper Limb Amputation Below Elbow

Study ID

NCT07850544

Start date

Dec 5, 2025

Status verified date

Sep, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Aged 18 years or older
  • Unilateral transradial level limb difference
  • Current or past user of myo-electric controlled prostheses
  • Six months or more post-amputation
  • Have adequate limb length such that a wrist rotation device can fit in the check socket
  • Have adequate limb length and diameter such that at least 9 channels of electrodes fit without cross pairing
  • Well-fitting socket as determined by a Socket-Comfort Score of 6 or above
  • Capable of wearing and operating a prosthesis with a wrist rotator and multi-articulating hand
  • Capable of understanding and following multi-step instructions and completing the tasks as described
  • English speaking

Exclusion Criteria:

  • Significant new injury that would prevent use of a prosthesis: The ability to consistently wear a prosthesis and perform activities of daily living and specific performance tasks is necessary to evaluate the relative benefits of the interventions.
  • Cognitive impairment that would adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential for the study to generate useable, reliable data. The ability to obtain relevant user feedback through questionnaires and informal discussion adds significant value to this study.
  • Significant other comorbidity: Any other medical issues or injuries that would preclude completion of the study, use of the prostheses, or that would otherwise prevent acquisition of useable data by researchers.
  • Pregnant participants as risk to pregnant individuals, embryos, or fetuses are not understood.

Study Design

Enrollment

32 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Sequence 1

Each arm will test all 4 conditions but in a different order from each other.

experimental: Sequence 2

Each arm will test all 4 conditions but in a different order from each other.

experimental: Sequence 3

Each arm will test all 4 conditions but in a different order from each other.

experimental: Sequence 4

Each arm will test all 4 conditions but in a different order from each other.

Interventions

Condition A: Electrode Configuration

Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

Condition B: Electrode Configuration

Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

Condition C: Electrode Configuration

Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

Condition D: Electrode Configuration

Each intervention is a specific blinded number and location of electrodes within the prosthetic arm used to control the prosthetic arm with pattern recognition myoelectric control.

Primary outcome measure

  • ACMC [ Time Frame: 10 Minute task during each condition's site visit. ]

Central Contacts and Locations

Central contacts

Craig M Kelly

508-893-6363craig.kelly@liberatingtech.com

Locations

Shirley Ryan AbilityLab

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Craig M Kelly

508-893-6363craig.kelly@liberatingtech.com

Liberating Technologies, Inc. (LTI)

Recruiting

Holliston, Massachusetts, United States, 01746

Contacts

Craig M Kelly

508-893-6363craig.kelly@liberatingtech.com

More Information

Sponsor

Liberating Technologies, Inc.

Last update posted

Sep 30, 2026

Last verified

Sep, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-01. This information was provided to ClinicalTrials.gov by Liberating Technologies, Inc. on 2026-09-30. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.