Recruiting
Phase 1

Silverlon®

Sponsor:

State University of New York - Upstate Medical University

Code:

NCT07856732

Conditions

Head and Neck Cancer

Radiation Dermatitis Acute

Radiation Treatment

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Silverlon®

Study Details

Brief summary:

The purpose of this study is to determine if prophylactic silver-nylon burn dressing Silverlon® prevents a severe skin reaction under tracheostomy collars. It also aims to establish whether patients can tolerate Silverlon® under their tracheostomy with daily removal and weekly changes.

Conditions

Head and Neck Cancer

Radiation Dermatitis Acute

Radiation Treatment

Study ID

NCT07856732

Start date

Aug 30, 2026

Status verified date

Aug, 2026

Completion date

Jan 30, 2028

Anticipated

Primary completion date

Aug 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Undergoing definitive head and neck cancer (>4 weeks of treatment)
  • Have a tracheostomy
  • Age ≥ 18 years
  • Must be able to understand and write English

Exclusion Criteria:

  • Inability to fulfill requirements of the protocol
  • Presence of unhealed surgical wounds
  • Subjects unable or unwilling to wear Silverlon dressings
  • Active infection of treatment area
  • Any co-morbidity or condition which, in the opinion of the investigator, may interfere with the assessments and procedures of this protocol.
  • Subjects with known sensitivity to silver or nylon.

Study Design

Enrollment

10 participants

Anticipated

Intervention Model

Single group

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Using Silverlon®

Patients will be given Silverlon®

Interventions

Silverlon®

Silverlon® is a specialized, antimicrobial wound dressings that is approved in radiation dermatitis. The study is aimed at determining if this dressing is effective in prophylactically preventing dermatitis in high risk patients.

Primary outcome measure

  • Feasibility of Silveron dressing [ Time Frame: 7 weeks ]

Central Contacts and Locations

Central contacts

Karna Sura, MD

315-464-5276surak@upstate.edu

Locations

Upstate Medical University

Recruiting

Syracuse, New York, United States, 12310

Contacts

Karna Sura, MD

315-464-5276surak@upstate.edu

More Information

Sponsor

State University of New York - Upstate Medical University

Last update posted

Oct 5, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-06. This information was provided to ClinicalTrials.gov by State University of New York - Upstate Medical University on 2026-10-05. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.