Recruiting

MAVEN & Alpha Omega

Sponsor:

Mayo Clinic

Code:

NCT07868614

Conditions

Essential Tremor

Parkinson's Disease

Dystonia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Multifunctional Apparatus for Voltammetry, Electrophysiology, and Neuromodulation (MAVEN)

Study Details

Brief summary:

The purpose of this research is to determine if the electrophysiologic data collected from standard-of-care microelectrode recordings during human deep brain stimulation (DBS) surgery will be the same using the MAVEN device compared with the standard Alpha Omega device with either a tungsten standard-of-care microelectrode (for microelectrode recordings), or a carbon-fiber microelectrode (for neurotransmitter recordings). The number of microelectrodes used for both the tungsten and the carbon-fiber version will be the same as the standard-of-care.

Conditions

Essential Tremor

Parkinson's Disease

Dystonia

Study ID

NCT07868614

Start date

Jul 29, 2025

Status verified date

Oct, 2026

Completion date

Dec 1, 2028

Anticipated

Primary completion date

Dec 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Mayo Clinic patients already scheduled to undergo DBS surgery with Dr. Kendall Lee fora movement disorder.

Exclusion Criteria:

  • Patients not approved for DBS surgery by the multidisciplinary DBS committee.

Study Design

Enrollment

30 participants

Anticipated

Interventions and Outcome Measures

Arms

Tungsten fiber microelectrode

Standard of care Tungsten microelectrode and cables will be utilized, and a splitter adaptor cable will route the data to both the standard Alpha Omega device and also to MAVEN, for comparison of MER readings.

Carbon fiber microelectrode

A carbon fiber microelectrode will be utilized (in lieu of the tungsten microelectrode) and a splitter adaptor cable will route the data to both the standard Alpha Omega device and also to MAVEN, for comparison of MER readings.

Interventions

Multifunctional Apparatus for Voltammetry, Electrophysiology, and Neuromodulation (MAVEN)

During deep brain stimulation (DBS) surgery, the MAVEN device will be used in parallel with the currently used Alpha Omega Device to compare the quality of electrophysiologic readings.

Primary outcome measure

  • Agreement between MAVEN device and Alpha Omega device [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Neurosurgery Study Team

507-293-7354lee.kendall@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Neurosurgery Study Team

507-293-7354

Principal Investigator:

Kendall Lee, M.D.

More Information

Sponsor

Mayo Clinic

Last update posted

Oct 9, 2026

Last verified

Oct, 2026

Keywords

  • Deep brain stimulation surgery

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-10-09. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.