Recruiting

Antimicrobial Resistance

Sponsor:

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Code:

NCT07874139

Conditions

Chronic Lung Diseases

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This observational, multicentric prospective study aims to understand the prevalence and burden of antimicrobial resistance (AMR) in people with chronic lung diseases (CLD) across the globe, understanding also geographical variability and the risk factors for acquiring AMR.

The primary objective is to understand the prevalence and burden of AMR in CLD both at a local and gloval level.

Secondary objectives include: 1) understanding susceptibilities models of high priority pathogens in people with CLD; 2) understanding geographic variability in the prevalence of AMR in CLD; 3) analysing risk factors for AMR in CLD Participants will be recruited

Conditions

Chronic Lung Diseases

Study ID

NCT07874139

Start date

Mar 31, 2025

Status verified date

Oct, 2026

Completion date

Nov, 2029

Anticipated

Primary completion date

Nov, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients of all ages with any chronic lung disease who, for clinical practice, underwent testingof at least one respiratory biological sample (sputum culture; bronchoaspirate; bronchoalveolar lavage; nasal swab; throat swab) within the 12 months prior to the visit.
  • Patients attending an outpatient clinic or hospitalized during the study period

Exclusion Criteria:

  • Patients who have not signed the informed consent form
  • Absence of data in the patient record

Study Design

Enrollment

683 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Prevalence of antimicrobial resistance in chronic lung diseases [ Time Frame: Five years from the beginning of the study. ]

Central Contacts and Locations

Central contacts

Andrea Gramegna

0255032020andrea.gramegna@unimi.it

Chiara Premuda

0255032020chiara.premuda@policlinico.mi.it

Locations

University of Michigan

Recruiting

Ann Arbor, Michigan, United States, 48109

Foothills Medical Centre

Recruiting

Calgary, Canada

More Information

Sponsor

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Last update posted

Oct 14, 2026

Last verified

Oct, 2026

Keywords

  • AMR
  • antimicrobial resistance
  • chronic lung disease
  • chronic respiratory disease
  • chronic pulmonary disease
  • chronic respiratory conditions
  • high-priority pathogens

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-15. This information was provided to ClinicalTrials.gov by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico on 2026-10-14. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.