Recruiting

Chatbot Assessment

Sponsor:

Roswell Park Cancer Institute

Code:

NCT07887620

Conditions

Hereditary Breast Carcinoma

Hereditary Malignant Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Text Message -based Navigation Intervenion

Artificial Intelligence based Intervention

Study Details

Brief summary:

This clinical trial studies whether a chatbot can be used to help collect medical history and perform cancer risk assessment among patients undergoing cancer genetic counseling. With the improved cost of genetic testing and growing utilization of genetics in cancer care and risk assessment, there is growing pressure placed on certified genetic counselors. To address this issue, many have turned to artificial intelligence (the branch of computer science that deals with writing computer programs that can solve problems creatively) for practical solutions to re-distribute the workload of certified genetic counselors. The chatbot in this trial uses artificial intelligence technology to analyze information provided by the patient during a phone call. The chatbot then generates a family history summary, family tree (pedigree), and cancer risk related assessments, which may help redistribute the workload for the certified genetic counselor and ultimately make genetic counseling more accessible. Using a chatbot may be helpful in collecting medical history and determining cancer risk assessment among patients undergoing cancer genetic counseling.

Conditions

Hereditary Breast Carcinoma

Hereditary Malignant Neoplasm

Study ID

NCT07887620

Start date

Nov 1, 2026

Status verified date

Oct, 2026

Completion date

Nov 1, 2027

Anticipated

Primary completion date

Nov 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • PATIENT PARTICIPANTS: Age 18 years or greater
  • PATIENT PARTICIPANTS: Scheduled as a new patient appointment to see a certified genetic counselor at the Roswell Park Comprehensive Cancer Center (either in person or for a virtual appointment)
  • PATIENT PARTICIPANTS: Written and spoken fluency in English
  • PATIENT PARTICIPANTS: Able to understand the consenting process and willing to participate in the study
  • GENETIC COUNSELOR PARTICIPANTS: Any genetic counselor who sees patients for initial genetics consultation at Roswell Park Comprehensive Cancer Center is eligible to participate in the study

Exclusion Criteria:

  • Prior germline genetic testing for a hereditary cancer predisposition
  • First or second-degree family member with a known pathogenic variant, likely pathogenic variant, or variant of uncertain significance in a gene associated with cancer predisposition
  • Scheduled to see a genetic counselor who has not give

Study Design

Enrollment

129 participants

Anticipated

Intervention Model

Single group

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Screening - chatbox call

Patients receive a text message with chatbot phone number at baseline. Patients then complete a phone call with the chatbot over 10-20 minutes consisting of a structured, genetics-specific interview and receive a chatbot generated provider summary, pedigree/structured data, NCCN flag, and Tyler-Cuzick score, which are routed to clinical team up to 21 days before scheduled genetics appointment.

Interventions

Text Message -based Navigation Intervenion

Receive chatbot phone number text message

Artificial Intelligence based Intervention

Complete chatbot phone call

Primary outcome measure

  • Sensitivity and specificity of chatbot in determining if patient meets National Comprehensive Cancer Network (NCCN) criteria for germline genetic testing [ Time Frame: Up to 21 days before genetics appointment ]

Central Contacts and Locations

Locations

Roswell Park Comprehensive Cancer Center

Recruiting

Buffalo, New York, United States, 14203

Contacts

ASK RPCI

877-275-7724AskRoswell@Roswellpark.org

More Information

Sponsor

Roswell Park Cancer Institute

Last update posted

Oct 27, 2026

Last verified

Oct, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-28. This information was provided to ClinicalTrials.gov by Roswell Park Cancer Institute on 2026-10-27. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.