Recruiting

Transcatheter Aortic Valve Replacement

Sponsor:

American College of Cardiology

Code:

NCT07908355

Conditions

Aortic Valve Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Transcatheter Aortic Valve Replacement

Study Details

Brief summary:

The STS/ACC TVT Registry™ (TVT Registry), created by The Society of Thoracic Surgeons (STS) and the American College of Cardiology Foundation (ACCF), is a benchmarking tool designed to assess the prevalence, demographics, management, and outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) procedure. Patient-level data will be submitted by participating hospitals to the TVT Registry via the American College of Cardiology Foundation's National Cardiovascular Data Registry (NCDR). The primary aims of the TVT Registry, are to optimize the outcomes and management of patients through the implementation of evidence-based guideline recommendations in clinical practice, facilitate efforts to improve the quality and safety for patients undergoing TAVR procedures, investigate novel quality improvement methods and provide risk-adjusted assessment of patients for comparison with nationwide NCDR data. The secondary purpose of the TVT Registry is to serve as a rich source of clinical data to support assessments of short- and long-term safety, comparative and cost effectiveness research, and as a scalable data infrastructure for pre and post market studies.

Conditions

Aortic Valve Stenosis

Study ID

NCT07908355

Start date

Sep, 2026

Status verified date

Oct, 2026

Completion date

Jan, 2036

Anticipated

Primary completion date

Jan, 2036

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients 18 years or over on arrival at the facility undergoing transcatheter aortic valve replacement.

Exclusion Criteria:

\-

Study Design

Enrollment

50000 participants

Anticipated

Interventions and Outcome Measures

Arms

Transcatheter Aortic Valve Replacement Patients

TAVR Patients Will include all patients 18 years or over who undergo Transcatheter Aortic Valve Replacement (TAVR) including patients with asymptomatic severe aortic stenosis. The sample size will include all patients entered into the TVT Registry.

Interventions

Transcatheter Aortic Valve Replacement

Procedure: Transcatheter Aortic Valve Replacement

• Minimal invasive implantation of a biological prothesis in Aortic Position

Primary outcome measure

  • 30 Day Major Adverse Cardiac and Cerebrovascular Events [ Time Frame: 30 days post procedure ]

Central Contacts and Locations

Locations

American College of Cardiology / National Cardiovascular Data Registry

Recruiting

Washington D.C., District of Columbia, United States, 20037

Contacts

NCDR Product Support

1-800-257-4737ncdr@acc.org

More Information

Sponsor

American College of Cardiology

Last update posted

Nov 2, 2026

Last verified

Oct, 2026

Keywords

  • STS/ACC TVT Registry™
  • TVT Registry

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-03. This information was provided to ClinicalTrials.gov by American College of Cardiology on 2026-11-02. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.