CEUSThe Use of Contrast Enhanced Ultrasound (CEUS) In Post-Surgical Pancreatic Cancer Patients to Evaluate Local Disease Recurrence

Inclusion Criteria:

• Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:

1. Be a patient that underwent surgical resection of PDAC located in the head or body of the pancreas and are being followed for recurrence with CT imaging as part of their standard of care.
2. Be 18 years of age or older.
3. If the subject is of child-bearing potential, must have a negative pregnancy test.
4. Be conscious and able to comply with study procedures.
5. Have read and signed the IRB approved consent form for participating in the study.

Exclusion Criteria:

• An individual who meets any of the following criteria will be excluded from participation in this study:

1. Females who are pregnant or nursing.
2. Patients who have received an investigational drug in the 30 days before study drug administration or will receive one within 72 hours afterwards.
3. Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable. For example:

• Patients on life support or in a critical care unit.
• Patients with clinically unstable cardiopulmonary conditions (acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure, or serious ventricular arrhythmias)
• Patients with recent cerebral hemorrhage (within 1 month).

4. Patients who have undergone surgery within 24 hours prior to the study ultrasound imaging examination.
5. Patients with congenital heart defects.
6. Patient with a known allergy to Lumason.