Recruiting

Observational Study

Sponsor:

Pediatric Nephrology Research Consortium

Code:

NCT07931170

Conditions

IgA Nephropathy (IgAN)

IgA Vasculitis

Idiopathic Immune Complex Glomerulonephritis

C3 Glomerulopathy

Membranous Nephropathy

Eligibility Criteria

Sex: All

Age: 0 - 18

Healthy Volunteers: Not accepted

Study Details

Brief summary:

To review and collect information from a patients medical record in order to study and research how to help other children with glomerular diseases.

Conditions

IgA Nephropathy (IgAN)

IgA Vasculitis

Idiopathic Immune Complex Glomerulonephritis

C3 Glomerulopathy

Membranous Nephropathy

Study ID

NCT07931170

Start date

Oct 1, 2026

Status verified date

Nov, 2026

Completion date

Jun, 2032

Anticipated

Primary completion date

Dec, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 18

Healthy Volunteers: Not accepted

Inclusion Criteria:

Children with biopsy-proven glomerular disease or populations with a clinical diagnosis of glomerular disease

Exclusion Criteria:

Patients who declined (or unable to provide informed consent, + informed assent of minors) to participate Patients with End Stage Kidney Disease (Stage 5 CKD, eGFR < 15mL/min/1.73m2)

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Arms

IgA Nephropathy (with biopsy)

Subjects diagnosed with IgA Nephropathy less than 18 years of age

IgA Vasculitis (with biopsy)

Subjects diagnosed with IgA Vasculitis less than 18 years of age

Idiopathic Immune Complex Glomerulonephritis (with biopsy)

Subjects diagnosed with Idiopathic Immune Complex Glomerulonephritis less than 18 years of age

C3 Glomerulopathy (with biopsy)

Subjects diagnosed with C3 Glomerulopathy less than 18 years of age

Membranous Nephropathy (with biopsy)

Subjects diagnosed with Membranous Nephropathy less than 18 years of age

Focal and Segmental Glomerulosclerosis (with biopsy)

Subjects diagnosed with Focal and Segmental Glomerulosclerosis less than 18 years of age

Minimal Change Disease (with biopsy)

Subjects diagnosed with Minimal Change Disease less than 18 years of age

Anti-Neutrophilic Cytoplasmic antibody-GN (ANCA) (with biopsy)

Subjects diagnosed with Anti-Neutrophilic Cytoplasmic antibody-GN (ANCA) less than 18 years of age

Lupus Nephritis (with biopsy)

Subjects diagnosed with Lupus Nephritis less than 18 years of age

Alport Syndrome (with biopsy)

Subjects diagnosed with Alport Syndrome less than 18 years of age

Infection-related or post-infectious Glomerulonephritis (with or without biopsy)

Subjects diagnosed with Infection-related or post-infectious Glomerulonephritis (with or without biopsy) less than 18 years of age

Idiopathic Nephrotic Syndrome (with or without biopsy)

Subjects diagnosed with Idiopathic Nephrotic Syndrome (with or without biopsy) less than 18 years of age

Primary outcome measure

  • Proteinuria, and change over time thereof (urine protein-creatinine ratio) [ Time Frame: Baseline and follow up timepoints (every 6 months) post-diagnosis to be reviewed at end of years 1 and 2 of data collection ]

Central Contacts and Locations

Central contacts

Amy Dutcher, MCR

6145547621adutcher@PNRConsortium.org

Teri Crumb, MSN, RN, CCRC

616-607-4430teri@pnrconsortium.org

Locations

Boston Children's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Contacts

Natalie Pursel

617-355-6762getpluggedin@pnrconsortium.org

Swethapriya Damagatla

617-355-6762getpluggedin@pnrconsortium.org

Principal Investigator:

Ankana Daga, MD

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229

Contacts

Libby Siry, CRP

513.517.1439getpluggedin@pnrconsortium.org

Nina Kanis, CRC

513.517.1439getpluggedin@pnrconsortium.org

Principal Investigator:

Elif Erkan, MD

More Information

Sponsor

Pediatric Nephrology Research Consortium

Last update posted

Nov 12, 2026

Last verified

Nov, 2026

Keywords

  • Glomerular
  • Glomerular Disease
  • Nephritis
  • Nephropathy
  • Minimal Change
  • Alport
  • ANCA
  • Lupus
  • Membranous
  • C3G
  • Glomerulopathy
  • IgA

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-13. This information was provided to ClinicalTrials.gov by Pediatric Nephrology Research Consortium on 2026-11-12. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.