Recruiting

Written Exposure Therapy

Sponsor:

Brigham and Women's Hospital

Code:

NCT07935070

Conditions

PTSD (Childbirth-Related)

PTSD - Post Traumatic Stress Disorder

PTSD

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Written Exposure Therapy

Study Details

Brief summary:

In this research study, the investigators hope to determine whether Written Exposure Therapy is a feasible intervention for postpartum women experiencing trauma symptoms related to childbirth to complete. Written Exposure Therapy involves five structured psychotherapy sessions that can be conducted over telehealth.

Conditions

PTSD (Childbirth-Related)

PTSD - Post Traumatic Stress Disorder

PTSD

Study ID

NCT07935070

Start date

Feb 11, 2026

Status verified date

Nov, 2026

Completion date

Aug 31, 2027

Anticipated

Primary completion date

Jul 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Birthing individuals
  • 18 years of age or older
  • Living in Massachusetts
  • Can read, write, and speak English
  • Identified a traumatic event exposure related to their childbirth experience
  • Are between one month to two years postpartum
  • Have a probable CB-PTSD diagnosis based on a PCL-5 score ≥ 28.

Exclusion Criteria:

  • Current engagement in another form of trauma-focused psychotherapy
  • No or little memory of the traumatic event
  • Safety concerns including active suicidality, active psychosis, and heavy substance use with inability to cease substance use for at least 2 hours before and after each session.

Study Design

Enrollment

15 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Written Exposure Therapy

Interventions

Written Exposure Therapy

Written exposure therapy (WET) is a highly protocolized evidence-based brief psychotherapeutic intervention for the treatment of post-traumatic stress disorder (PTSD).

Primary outcome measure

  • Feasibility (retention rate) [ Time Frame: From date of the first WET session until the date of the fifth WET session, withdrawal from the study, or determination of loss to follow-up, whichever occurs first (estimated average assessment period: 6 weeks). ]
  • Feasibility (Engagement rate) [ Time Frame: From the date of enrollment until the date of the first WET session, withdrawal from the study, or determination of loss to follow-up, whichever occurs first (estimated average assessment period: 4 weeks). ]
  • Acceptability (Credibility) [ Time Frame: Baseline ]
  • Acceptability (Satisfaction) [ Time Frame: Study exit survey approximately 4 weeks after final WET session. ]

Central Contacts and Locations

Central contacts

Amanda Koire, MD, PhD

(617) 525-3707akoire@bwh.harvard.edu

Locations

Brigham and Women's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Contacts

Amanda Koire, MD, PhD

617-525-3707mgbscribe@mgb.org

More Information

Sponsor

Brigham and Women's Hospital

Last update posted

Nov 13, 2026

Last verified

Nov, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-11-14. This information was provided to ClinicalTrials.gov by Brigham and Women's Hospital on 2026-11-13. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.