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Anemia Clinical Trials

Browse 262 anemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Congenital Hemolytic and Dyserythropoietic Anemias

for
Hemolytic Anemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT07649213

Recruiting

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

for
Aplastic Anemias, Hemoglobinopathies, Bone Marrow Failure
Location: New York NY, Richmond VA, Durham NC, Gainesville FL,
Sponsor: Medical College of Wisconsin

Sex: All

Age: 0+

Code: NCT07227155

Recruiting

Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement Evaluation

for
Varus-Derotation Osteotomy Surgery, Iron-deficiency Anemia,
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 0 - 18

Code: NCT07095244

Recruiting

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

for
Sickle Cell Disease, Sickle Cell Anemia, Osteonecrosis,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18 - 70+

Code: NCT06016634

Phase2, Recruiting

Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease

for
Sickle Cell Disease, Measles Vaccination, Sickle Cell Anemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 6

Code: NCT07356050

Recruiting

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A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency

for
Anemia, Decreased Glomerular Filtration Rate
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT05735314

Recruiting

A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

for
Paroxysmal Nocturnal Hemoglobinuria (PNH), Persistent Anemia
Location: Toronto
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07187401

Phase1, Phase2, Recruiting

Two Step Haplo With Radiation Conditioning

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Philadephia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05031897

Phase2, Recruiting

Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

for
Sickle Cell Disease, Sickle Cell Anaemia, Sickle Cell Anemia
Location: Toronto
Sponsor: Biossil Inc.

Sex: All

Age: 16 - 35

Code: NCT07282210

Phase2, Recruiting

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

for
Sickle Cell Disease, Hemolytic Anemia
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT07566494

Phase1, Recruiting

Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

for
Warm Autoimmune Hemolytic Anemia (WAIHA),
Location: Rochester MN, Omaha NE
Sponsor: CRISPR Therapeutics AG

Sex: All

Age: 18+

Code: NCT07549698

Phase1, Phase2, Recruiting

Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS)

for
Diamond Blackfan Anemia
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 3 - 30

Code: NCT07186179

Recruiting

Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)

for
Sickle Cell Anemia (HbSS), Sickle-β0-thalassemia (HbSβ0)
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT07177300

Recruiting

Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia

for
RPS19 Deficient Diamond-Blackfan Anemia
Location: Boston MA, Stanford CA
Sponsor: Apriligen, Inc.

Sex: All

Age: 2 - 25

Code: NCT07476183

Phase1, Recruiting

A Study of Emapalumab for Pediatric Aplastic Anemia

for
Aplastic Anemia, Cytopenia, Hypocellular Marrow
Location: New York NY, Philadelphia PA, Richmond VA,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0 - 25

Code: NCT06430788

Phase2, Recruiting

To Assess Safety of Mitapivat and Provide Proof of Concept of the Efficacy of the Drug in Patients With RBC Membranopathies or CDAII.

for
Anemia
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07055243

Phase2, Recruiting

Role of Acetaldehyde in the Development of Oral Cancer

for
Alcohol-Related Carcinoma, Fanconi Anemia,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18 - 45

Code: NCT05973656

Recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

for
Sickle Cell Disorders, Sickle Cell Disease, Hemoglobin S,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 65

Code: NCT05904093

Phase1, Recruiting

Endoscopic Evaluation for Iron Deficiency Anemia in Patients on Antithrombotic Therapy

for
Obscure Gastrointestinal Bleeding, Iron-Deficiency Anemia,
Location: Trois-Rivieres
Sponsor: Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec

Sex: All

Age: 18 - 70+

Code: NCT07089030

Recruiting

Kids With Iron Deficiency and Scoliosis

for
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis,
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 10 - 26

Code: NCT06042699

Recruiting

What are Anemia clinical trials?

Anemia clinical trials rarely take a one-size-fits-all approach, since the condition itself can stem from so many different causes, like low iron, vitamin deficiencies, chronic illness, or inherited blood conditions. Each study usually zeroes in on a specific cause or type, testing ways to restore healthy red blood cell levels or address whatever's driving the deficiency in the first place.

Researchers also use this research to look at how anemia affects everyday life beyond blood test numbers, since fatigue and low energy can quietly impact work, activity levels, and overall wellbeing long before someone even realizes something's wrong.

The importance of clinical trials in Anemia research

Anemia is one of the most common blood conditions worldwide, yet its causes and impact vary so much from person to person that research has to work hard to keep up. Anemia research studies help fill that gap by studying different types of anemia individually, rather than approaching it as a single condition with one explanation.

This kind of research also helps connect the dots between anemia and other health conditions it's often tied to, like chronic kidney disease or pregnancy-related changes, giving researchers a fuller picture of how blood health fits into someone's overall wellbeing.

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Iron deficiency is especially common during pregnancy. Learn more in our article

Iron Deficiency During Pregnancy: Symptoms, Risks, and Treatment Options

Who can participate in Anemia clinical trials?

Types of Anemia clinical trials

How to enroll in a clinical trial for Anemia