Browse 244 bipolar disorder clinical trials enrolling across the United States and Canada. 82 people applied to bipolar disorder studies last month. Search by city or state to find one near you.
Bipolar disorder is marked by swings between mania and depression, and for most people the depressive episodes are the longest and hardest part. Standard antidepressants on their own can trigger mania, so bipolar depression needs its own treatments, and there are still relatively few. Many people try several medicines before finding one that works with tolerable side effects.
Sponsor: National Institute of Mental Health (NIMH)
Sex: All
Age: 3 - 70+
Code: NCT00024635
Recruiting
Active & Responsive
Three-level Model of DBT-informed Care for Youth With and/or at Familial Risk for Bipolar Disorder (DB3)
for
Bipolar Disorder
Location: Toronto
Sponsor: Centre for Addiction and Mental Health
Sex: All
Age: 13 - 23
Code: NCT05153369
Recruiting
Active & Responsive
Healthy Lifestyles in Bipolar Disorder: Bay Area Study
for
Bipolar Disorder, Time Restricted Eating
Location: Berkeley CA
Sponsor: University of California, Berkeley
Sex: All
Age: 18 - 65
Code: NCT06555406
Recruiting
Active & Responsive
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
for
Borderline Personality Disorder (BPD),
Location: Toronto
Sponsor: Joshua Rosenblat
Sex: All
Age: 18 - 70
Code: NCT07569198
Phase 2, Recruiting
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Active & Responsive
Cannabidiol for Bipolar Depression (CBD-BD)
for
Bipolar Disorder
Location: Kingston, Hamilton, Vancouver
Sponsor: University of British Columbia
Sex: All
Age: 19 - 70
Code: NCT05867849
Phase 3, Recruiting
Active & Responsive
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
for
Bipolar II Depression
Location: Vancouver
Sponsor: Lakshmi N Yatham
Sex: All
Age: 19 - 65
Code: NCT06943573
Phase 2, Recruiting
Active & Responsive
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
for
Bipolar I Disorder, Bipolar II Disorder,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: All
Age: 18 - 65
Code: NCT07213466
Recruiting
Active & Responsive
Ketogenic Intervention for Bipolar Depression
for
Bipolar Depression
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: All
Age: 18 - 50
Code: NCT07121894
Recruiting
Active & Responsive
Safety and Feasibility of DBS for Bipolar Depression
for
Bipolar I Disorder, Bipolar Depression
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai
Sex: All
Age: 22 - 70
Code: NCT07745374
Recruiting
Active & Responsive
SYNCED - SYNChronized Eating in Bipolar Depression Study
for
Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
Location: Ottawa
Sponsor: University of Ottawa
Sex: All
Age: 18 - 55
Code: NCT06560957
Recruiting
Active & Responsive
Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
for
Bipolar Disorder
Location: Houston TX
Sponsor: Joao L. DeQuevedo
Sex: All
Age: 22 - 70+
Code: NCT04080778
Recruiting
Active & Responsive
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
for
Bipolar Disorder Type I With Mania
Location: New Haven CT, Staten Island NY, Marlton NJ,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18 - 65
Code: NCT06929273
Phase 3, Recruiting
Active & Responsive
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
for
Mania, Bipolar Disorder
Location: Staten Island NY, Boynton Beach FL, Savannah GA,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18 - 65
Code: NCT07140913
Phase 3, Recruiting
Active & Responsive
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder
for
Bipolar-I Disorder With Mania or Mania With Mixed Features
Location: New Haven CT, Staten Island NY, West Palm Beach FL,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18 - 65
Code: NCT06951698
Phase 3, Recruiting
Active & Responsive
Deep Brain Stimulation of Treatment-Resistant Bipolar Depression
for
Bipolar Depression
Location: Houston TX
Sponsor: Wayne Goodman MD
Sex: All
Age: 22 - 64
Code: NCT06599099
Recruiting
Active & Responsive
Natural History of Depression, Bipolar Disorder and Suicide Risk