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Bipolar Disorder Clinical Trials

Browse 113 bipolar disorder clinical trials enrolling across the United States and Canada. 83 people applied to bipolar disorder studies last month. Search by city or state to find one near you.

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Active & Responsive

Deep Brain Stimulation of Treatment-Resistant Bipolar Depression

for
Bipolar Depression
Location: Houston TX
Sponsor: Wayne Goodman MD

Sex: All

Age: 22 - 64

Code: NCT06599099

Recruiting
Active & Responsive

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

for
Bipolar II Disorder,
Location: San Francisco CA
Sponsor: Andrew Krystal

Sex: All

Age: 22 - 70

Code: NCT07127913

Recruiting
Active & Responsive

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

for
Bipolar II Disorder, Depression, Bipolar, Suicidality
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 25 - 70

Code: NCT06706232

Phase 2, Recruiting
Active & Responsive

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

for
Unipolar Depression, Bipolar Depression
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 65

Code: NCT07266545

Recruiting
Active & Responsive

Natural History of Depression, Bipolar Disorder and Suicide Risk

for
Behavioral Symptoms, Suicide, Self-Injurious Behavior,
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 18 - 70+

Code: NCT06462196

Recruiting

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Active & Responsive

Healthy Lifestyles for Bipolar Disorder

for
Time Restricted Eating, Diet, Mediterranean
Location: Berkeley CA
Sponsor: University of California, Berkeley

Sex: All

Age: 18 - 65

Code: NCT06188754

Recruiting
Active & Responsive

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

for
Depression, Alcoholism, Drug Abuse
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 64

Code: NCT02604277

Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

for
Bipolar-I Disorder With Mania or Mania With Mixed Features
Location: New Haven CT, Staten Island NY, West Palm Beach FL,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT06951698

Phase 3, Recruiting
Active & Responsive

CLOZAPINE Response in Biotype-1

for
Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder
Location: Boston MA, Hartford CT, Athens GA, Chicago IL,
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 60

Code: NCT04580134

Recruiting
Active & Responsive

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

for
Schizophrenia Spectrum and Other Psychotic Disorders,
Location: Boston MA, Belmont MA, Hartford CT, Athens GA,
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 18 - 40

Code: NCT06740383

Recruiting
Active & Responsive

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

for
Bipolar II Depression
Location: Vancouver
Sponsor: Lakshmi N Yatham

Sex: All

Age: 19 - 65

Code: NCT06943573

Phase 2, Recruiting
Active & Responsive

An Innovative Master Platform for Clinical Trials in Mood Disorders

for
Mood Disorders, Depressive Disorder,
Location: Halifax, Ottawa, Kingston, Whitby, Toronto, Hamilton,
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 16+

Code: NCT06408012

Recruiting

Behavioural Activation Therapy for Bipolar Disorder

for
Bipolar Disorder
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18 - 65

Code: NCT04317859

Recruiting

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study

for
Major Depressive Disorder, Bipolar Disorder,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06897670

Recruiting

Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

for
Schizophrenia, Bipolar Disorder, Depressive Disorder, Major,
Location: Minneapolis MN
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05491538

Recruiting

Cerebellar Modulation of Cognition in Psychosis

for
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder I,
Location: Boston MA, Belmont MA
Sponsor: Mclean Hospital

Sex: All

Age: 18 - 55

Code: NCT06107764

Recruiting

Enhancing Rehabilitation for Veterans With Serious Mental Illness

for
Schizophrenia, Psychosis, Serious Mental Illness, PTSD,
Location: San Diego CA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18 - 70+

Code: NCT06586164

Recruiting

Taking Action for College Students

for
Major Depressive Disorder, Bipolar Disorder, Schizophrenia
Location: Philadelphia PA
Sponsor: Temple University

Sex: All

Age: 18+

Code: NCT06700902

Recruiting

Greater Houston Area Pediatric Bipolar Registry

for
Pediatric Bipolar Disorder
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 6 - 17

Code: NCT06665984

Recruiting

NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder

for
Bipolar Disorder, Major Depression, Migraine
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 8 - 70

Code: NCT05669703

Recruiting
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Interested in learning more about bipolar disorder in teens? Read our guide: Bipolar in Teens: What Parents Should Know About Treatment and Support

Raising a Teen with Bipolar? Here’s What’s Working Today