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A Study of Patritumab Deruxtecan (HER3-DXd) in Combination With Trastuzumab Deruxtecan (T-DXd) in Participants With HR-Positive, HER2-Low or HER2-Ultralow Unresectable or Metastatic Breast Cancer
for
Hormone Receptor Positive, HER2-low or HER2-ultralow,
Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial
for
Recurrent Prostate Adenocarcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: Male
Age: 18+
Code: NCT07650240
Phase2, Recruiting
New
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease
for
Recurrent Small Cell Lung Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 70+
Code: NCT07509034
Phase1, Recruiting
New
A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer
for
Hormone Receptor Positive Early Breast Cancer
Location: Margate FL, Port Orange FL, Beverly Hills CA
Sponsor: Rovi Pharmaceuticals Laboratories
Sex: Female
Age: 18 - 70+
Code: NCT07401381
Phase1, Recruiting
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Boston MA, Horsham PA, Philadelphia PA, Richmond VA,
Location: Miami FL, Pittsburgh PA, Indianapolis IN, Houston TX,
Sponsor: KaliVir Immunotherapeutics
Sex: All
Age: 18+
Code: NCT06444815
Phase1, Recruiting
Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
for
Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer,
Location: St Louis MO, Westwood KS
Sponsor: Washington University School of Medicine
Sex: All
Age: 18+
Code: NCT06374459
Phase1, Phase2, Recruiting
Long-term Follow-up of Subjects Treated With CAR T Cells
for
Long Term Adverse Effects, CAR-T, Duty to Follow Up, Adult,
Location: Boston MA
Sponsor: Marcela V. Maus, M.D.,Ph.D.
Sex: All
Age: 18+
Code: NCT05024175
Recruiting
Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
for
Hormone Receptor-Positive Breast Cancer,
Location: Long Branch NJ, Elizabeth NJ, Newark NJ, Livingston NJ,
Sponsor: Rutgers, The State University of New Jersey
Sex: All
Age: 18+
Code: NCT06518837
Phase2, Recruiting
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors
for
Neuroendocrine Tumors Unresectable,
Location: Baltimore MD, Fairfax VA, Chapel Hill NC, Miami FL,
Sponsor: Perspective Therapeutics
Sex: All
Age: 18 - 70+
Code: NCT05636618
Phase1, Phase2, Recruiting
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
for
Feeding Patterns, Sleep, Glucose Intolerance
Location: Boston MA
Sponsor: Massachusetts General Hospital
Sex: All
Age: 18+
Code: NCT04737200
Recruiting
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)