Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Is Radiation-before-pathology a Feasible Approach in the Palliative Oncology Setting? A Pragmatic Clinical Trial
for
Cancer
Location: London
Sponsor: David Palma
Sex: All
Age: 18+
Code: NCT06156800
Recruiting
Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
for
Multiple Myeloma, Cancer
Location: Wilmington NC, Durham NC, Chapel Hill NC, Charlotte NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center
Sex: All
Age: 18+
Code: NCT05145400
Phase 2, Recruiting
BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia
for
Advanced Solid Tumor, TNBC - Triple-Negative Breast Cancer,
Location: New Haven CT, New York NY, The Bronx NY,
Sponsor: SillaJen, Inc.
Sex: All
Age: 18+
Code: NCT05768932
Phase 1, Recruiting
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
for
Advanced Solid Tumor, Non Small Cell Lung Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Synthekine
Sex: All
Age: 18+
Code: NCT05098132
Phase 1, Phase 2, Recruiting
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
for
Cancer
Location: Fairhaven MA, Norwich CT, York PA, East Syracuse NY,
Sponsor: Tempus AI
Sex: All
Age: 18 - 70+
Code: NCT06207032
Recruiting
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Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies
for
Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT05039632
Phase 1, Phase 2, Recruiting
PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis
Immune Profiling for Cancer Immunotherapy Response
for
Cancer, Tumor, Solid, Hematologic Malignancy, Blood Cancer
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center
Sex: All
Age: 18+
Code: NCT06116032
Recruiting
Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin
for
Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06576037
Phase 1, Recruiting
Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
for
Hematopoietic and Lymphoid System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: All
Age: 18+
Code: NCT06015932
Recruiting
Combination Therapy in Cancers With Mutations in DNA Repair Genes
Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies
Point of Care Ultrasound for the Detection of Esophageal Food Bolus
for
Esophageal Foreign Body, Esophageal Obstruction
Location: York PA
Sponsor: WellSpan Health
Sex: All
Age: 18+
Code: NCT06507670
Recruiting
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
for
Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Providence RI, New York NY, Montreal,
Sponsor: Bicara Therapeutics
Sex: All
Age: 18+
Code: NCT04429542
Phase 1, Recruiting
Tolerability of Utidelone Capsule in Patients With Advanced Solid Tumors
for
Advanced Solid Tumor
Location: Los Angeles CA
Sponsor: Biostar Pharma, Inc.
Sex: All
Age: 18+
Code: NCT05681000
Phase 1, Recruiting
LIFE Cancer Survivorship Database for Pediatric Cancer
for
Pediatric Cancer
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles
Sex: All
Age: 0+
Code: NCT01518400
Recruiting
An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
for
Advanced Solid Tumors
Location: Fairfax VA, Toronto, Pittsburgh PA, Huntersville NC,