Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.
for
Advanced Solid Tumors, Recurrent or Progressive Glioblastoma,
Location: Fairfax VA, Tampa FL, Houston TX, Duarte CA
Sponsor: Crossbow Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07779798
Phase 1, Recruiting
New
Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer
for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 70+
Code: NCT07667400
Phase 1, Phase 2, Recruiting
New
An Artificial Intelligence-Powered Supportive Care Chatbot to Address the Supportive Care Needs of Young Adult Cancer Survivors
for
Hematopoietic and Lymphatic System Neoplasm,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center
Sex: All
Age: 18 - 39
Code: NCT07772596
Recruiting
Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)
for
Brain Metastases, Cancer (With CNS Involvement)
Location: Charleston SC
Sponsor: Medical University of South Carolina
Sex: All
Age: 18+
Code: NCT07227610
Phase 2, Recruiting
Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial
for
Rectal Cancer Stage II, Rectal Cancer Stage III,
Location: Anchorage AK
Sponsor: Fred Hutchinson Cancer Center
Sex: All
Age: 21+
Code: NCT06802172
Recruiting
DOAC - Dosing Options in AntiCoagulation Prophylaxis
for
Cancer, VTE (Venous Thromboembolism)
Location: Burlington VT
Sponsor: University of Vermont
Sex: All
Age: 18+
Code: NCT07005024
Phase 3, Recruiting
Decoupling Immunotherapy Toxicity and Cancer Response
for
Tumor, Cardiovascular
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT07382752
Recruiting
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Philadelphia PA, Columbus OH,
Sponsor: Fate Therapeutics
Sex: All
Age: 18+
Code: NCT06241456
Phase 1, Recruiting
Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors
for
Advanced Solid Tumor
Location: Boston MA, New York NY, Washington D.C. DC, Durham NC,
Sponsor: OncoC4, Inc.
Sex: All
Age: 18+
Code: NCT06635785
Phase 1, Phase 2, Recruiting
Using Virtual Reality for Patients With Gastrointestinal Disease
The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial
for
Heart Failure, Cardiotoxicity, Cancer
Location: Toronto
Sponsor: University Health Network, Toronto
Sex: All
Age: 18 - 45
Code: NCT05023785
Recruiting
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer
for
Head and Neck Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre
Sex: All
Age: 0+
Code: NCT04428515
Recruiting
New MRI Biomarkers in Head and Neck Cancers
for
Head and Neck Cancer, Thyroid Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center
Sex: All
Age: 18+
Code: NCT03483337
Recruiting
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
for
Solid Tumors
Location: New Haven CT, Hackensack NJ, Los Angeles CA