Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Study of AVZO-021 in Patients With Advanced Solid Tumors
for
Advanced Solid Tumor, HR+/HER2- Breast Cancer,
Location: Mineola NY, New York NY, Sarasota FL, Portland OR,
Sponsor: Avenzo Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05867251
Phase 1, Phase 2, Recruiting
SLR-108 PET Imaging in Subjects With Metastatic Solid Tumors
for
Metastatic Solid Tumors
Location: Newport Beach CA
Sponsor: Solve Therapeutics
Sex: All
Age: 18+
Code: NCT07728942
Phase 1, Recruiting
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors
for
Solid Tumor
Location: Dallas TX
Sponsor: Abbisko Therapeutics Co, Ltd
Sex: All
Age: 18+
Code: NCT05244551
Phase 1, Recruiting
IMPACT: IMplementation of Physical Activity for Children and Adolescents on Treatment
for
Pediatric Cancer, Pediatric Hematology
Location: Edmonton, Calgary
Sponsor: University of Calgary
Sex: All
Age: 5 - 18
Code: NCT04956133
Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors, Colorectal Cancer
Location: New Brunswick NJ, Toronto, Atlanta GA, Ann Arbor MI,
Sponsor: Vividion Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06004245
Phase 1, Recruiting
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Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams
for
Malignant Solid Neoplasm
Location: Danville IL, Urbana IL, Mattoon IL, Effingham IL,
Sponsor: SWOG Cancer Research Network
Sex: All
Age: 18+
Code: NCT07278739
Recruiting
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples
for
Barrett Esophagus, Barretts Esophagus With Dysplasia,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic
Sex: All
Age: 18 - 70+
Code: NCT06071845
Recruiting
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
FOCUS for Pediatric Sickle Cell Disease and Cancer
for
Pediatric Cancer, Sickle Cell Disease, Quality of Life,
Location: Atlanta GA
Sponsor: Georgia State University
Sex: All
Age: 12 - 18
Code: NCT04075877
Recruiting
Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer
for
Stage 1 cT1b-T1cN0M0, Triple Negative Breast Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06318897
Phase 2, Recruiting
QTX3034 in Patients With KRAS G12D Mutation
for
Solid Tumors
Location: New Haven CT, The Bronx NY, New York NY, Fairfax VA,
Sponsor: Quanta Therapeutics
Sex: All
Age: 18+
Code: NCT06227377
Phase 1, Recruiting
A Phase I Open-Label, Single-Arm, Dose-Escalation Clinical and Pharmacology Study of CCI-001 as Monotherapy and in Combination With Standard Chemotherapy in Patients With Recurrent and/or Metastatic Solid Tumours
for
Cancer: Recurrent and/or Metastatic Solid Tumours
Location: Edmonton
Sponsor: PharmaMatrix Holdings Ltd
Sex: All
Age: 18+
Code: NCT04823897
Phase 1, Recruiting
Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies
for
Cancer
Location: Lexington KY
Sponsor: Rachel Miller
Sex: All
Age: 18+
Code: NCT03089554
Phase 2, Recruiting
A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors
for
Advanced Solid Tumors
Location: Grand Rapids MI, San Antonio TX, West Valley City UT
Sponsor: ModernaTX, Inc.
Sex: All
Age: 18+
Code: NCT06880549
Phase 1, Recruiting
A Study to Evaluate the Safety and Antitumor Activity of GS-1206 in Adults With Solid Tumors
for
Solid Tumor
Location: Grand Rapids MI, Dallas TX, San Antonio TX
Sponsor: Gilead Sciences
Sex: All
Age: 18+
Code: NCT07703878
Phase 1, Recruiting
A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.