Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy
for
Cancer
Location: Gainesville FL
Sponsor: University of Florida
Sex: All
Age: 18 - 70+
Code: NCT06246409
Recruiting
Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer
for
Advanced Cancer, Metastatic Cancer
Location: Manchester NH, Concord NH, New York NY, Spartanburg SC,
Sponsor: Alliance Foundation Trials, LLC.
Sex: All
Age: 21+
Code: NCT06963723
Recruiting
The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
for
Cancer
Location: The Bronx NY, Scranton PA, Dickson City PA,
Sponsor: Eastern Cooperative Oncology Group
Sex: All
Age: 18+
Code: NCT06756607
Recruiting
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
for
Advanced Solid Tumor, High Grade Serous Adenocarcinoma of Ovary,
Location: Providence RI, New Haven CT, New York NY, Baltimore MD,
Sponsor: Volastra Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05902988
Phase 1, Phase 2, Recruiting
Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically
for
Dysphagia, Head and Neck Cancer
Location: Toronto
Sponsor: University Health Network, Toronto
Sex: All
Age: 18+
Code: NCT06192771
Recruiting
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Comprehensive Health Assessment for My Plan: Initial Implementation Study (CHAMP Implementation Study)
for
Cancer, Older Adults
Location: Toronto
Sponsor: University of Toronto
Sex: All
Age: 70+
Code: NCT06464471
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
for
Solid Tumor
Location: New York NY, Tampa FL, Augusta GA, Chicago IL,
Sponsor: Eisai Inc.
Sex: All
Age: 18+
Code: NCT04300556
Phase 1, Phase 2, Recruiting
Study of Lunresertib Alone or in Combination With RP-3500 or Zedoresertib (Debio 0123) in Patients With Advanced Solid Tumors
for
Advanced Solid Tumor
Location: Boston MA, Providence RI, New Haven CT,
Sponsor: Debiopharm International SA
Sex: All
Age: 12+
Code: NCT04855656
Phase 1, Recruiting
Leading Healthy Eating and Activity Promotion Program
for
Cancer Survivor, Cancer, Oncology
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham
Sex: All
Age: 18 - 70+
Code: NCT06868524
Recruiting
A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors
for
Select Advanced Solid Tumors
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center
Sex: All
Age: 18+
Code: NCT06598371
Phase 1, Phase 2, Recruiting
Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
for
Malnutitrion, Cancer
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center
Sex: All
Age: 18+
Code: NCT07776704
Recruiting
Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial
for
Advanced Malignant Solid Neoplasm,
Location: Columbus OH
Sponsor: Yuanquan Yang
Sex: All
Age: 18+
Code: NCT06470971
Phase 2, Recruiting
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
for
Advanced Solid Tumors With KRAS G12C Mutations,
Location: Boston MA, Philadelphia PA, Fairfax VA, Detroit MI,
Sponsor: Frontier Medicines Corporation
Sex: All
Age: 18+
Code: NCT06244771
Phase 1, Phase 2, Recruiting
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
for
Metastatic Uveal Melanoma, Cutaneous Melanoma,
Location: Philadelphia PA, Durham NC, Cincinnati OH, Nashville TN,
Sponsor: IDEAYA Biosciences
Sex: All
Age: 18+
Code: NCT03947385
Phase 1, Phase 2, Recruiting
GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
for
Cancer
Location: San Francisco CA
Sponsor: Stanford University
Sex: All
Age: 8 - 18
Code: NCT05415007
Recruiting
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
for
Hodgkin Lymphoma in Remission, Leukemia in Remission,
Location: Scarborough ME, Boston MA, Providence RI, New Haven CT,
Sponsor: Children's Oncology Group
Sex: All
Age: 0+
Code: NCT01790152
Recruiting
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
for
Hematopoietic and Lymphoid System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic
Sex: All
Age: 18+
Code: NCT05530759
Recruiting
BRIDGE-SIC Efficacy Trial
for
Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute
Sex: All
Age: 18+
Code: NCT07735442
Recruiting
Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors
for
Advanced Solid Tumors
Location: North Haven CT, Ottawa, Toronto, Orlando FL,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.
Sex: All
Age: 18+
Code: NCT06384352
Phase 1, Recruiting
Unified Network for Integrated Fluid Collection at Yale