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Gastrointestinal Clinical Trials

Browse 1,492 gastrointestinal clinical trials enrolling across the United States and Canada. 173 people applied to gastrointestinal studies last month. Search by city or state to find one near you.

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Active & Responsive

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase 2, Recruiting
Active & Responsive

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

for
Colorectal Neoplasms, Breast Neoplasms, Head and Neck Neoplasms,
Location: Toms River NJ, Jersey City NJ, Belleville NJ, Newark NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT07158164

Recruiting
Active & Responsive

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

for
Early Rectal Cancer, Stage I Rectal Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07735624

Phase 2, Recruiting
Active & Responsive

Non-nutritive Sweeteners in Inflammatory Bowel Disease

for
Inflamatory Bowel Disease, Crohn Disease (CD)
Location: Chagrin Falls OH, Cleveland OH, Westlake OH
Sponsor: University Hospitals Cleveland Medical Center

Sex: All

Age: 18 - 70

Code: NCT07769437

Recruiting
Active & Responsive

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

for
Left-sided Colorectal Cancer
Location: Babylon NY, Savannah GA, Warner Robins GA,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07702032

Phase 3, Recruiting

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Active & Responsive

Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis

for
Colorectal Adenocarcinoma Metastatic in the Liver,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07764497

Phase 2, Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase 1, Phase 2, Recruiting
Active & Responsive

LRG GIST Patient Registry

for
GIST, GIST - Gastrointestinal Stromal Tumor,
Location: Wayne NJ
Sponsor: The Life Raft Group

Sex: All

Age: 0+

Code: NCT07697248

Recruiting
Active & Responsive

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

for
Localized Colon Carcinoma, Stage IIB Colon Cancer AJCC v8,
Location: Johns Creek GA, Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT07140679

Phase 2, Recruiting
Active & Responsive

APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)

for
Acute Uncomplicated Diverticulitis
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07492134

Phase 2, Recruiting
Active & Responsive

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

for
Colorectal Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07281768

Phase 2, Recruiting
Active & Responsive

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

for
Colorectal Cancer
Location: New York NY, Baltimore MD, Pittsburgh PA, Louisville KY,
Sponsor: Exero Medical Ltd.

Sex: All

Age: 21+

Code: NCT07337590

Recruiting
Active & Responsive

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor Malignancies, Colorectal Carcinoma,
Location: Philadelphia PA, Fairfax VA, Orlando FL,
Sponsor: Tasca Therapeutics

Sex: All

Age: 18+

Code: NCT07030257

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: New York NY, Hackensack NJ, Fairfax VA, Buffalo NY,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT07094204

Phase 1, Recruiting
Active & Responsive

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

for
Triple Negative Breast Cancer, HER2-negative Breast Cancer,
Location: Fairfax VA, Orlando FL, Huntersville NC, Sarasota FL,
Sponsor: Dren Bio

Sex: All

Age: 18+

Code: NCT06999187

Phase 1, Recruiting
Active & Responsive

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

for
Crohns Disease
Location: Hamilton, London, Cleveland OH, St Louis MO,
Sponsor: Alimentiv Inc.

Sex: All

Age: 18+

Code: NCT06670638

Recruiting
Active & Responsive

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

for
Perianal Fistula Due to Crohn's Disease
Location: New York NY, Philadelphia PA, Nashville TN, St Louis MO,
Sponsor: Direct Biologics, LLC

Sex: All

Age: 18 - 70+

Code: NCT06918808

Phase 2, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Boston MA, New York NY, Toronto, Hamilton, Tampa FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase 1, Recruiting
Active & Responsive

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer,
Location: Boston MA, Providence RI, Worcester MA, Hartford CT,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT06901531

Phase 3, Recruiting
Active & Responsive

Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis

for
Colitis, Ulcerative
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 18 - 64

Code: NCT06660693

Phase 3, Recruiting