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Gastrointestinal Clinical Trials

Browse 1,492 gastrointestinal clinical trials enrolling across the United States and Canada. 173 people applied to gastrointestinal studies last month. Search by city or state to find one near you.

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Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Cleveland OH,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase 1, Phase 2, Recruiting
Active & Responsive

Pelvic Health Electrically Evoked Recording (PEER) 2 Study

for
Overactive Bladder, Fecal Incontinence, Urinary Retention
Location: Cleveland OH, Hilliard OH, Indianapolis IN,
Sponsor: MedtronicNeuro

Sex: All

Age: 18+

Code: NCT05200923

Recruiting
Active & Responsive

Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) and Cemiplimab for Locally Advanced Biliary Tract Cancer (BTC)

for
Colon and Rectal Cancer
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT07433673

Phase 2, Recruiting
Active & Responsive

MagDI U.S. Registry

for
Anastomosis, Surgical, Internal Hernia, Bowel Obstruction
Location: Cary NC, Miami FL, Louisville KY, Lafayette LA,
Sponsor: GT Metabolic Solutions, Inc.

Sex: All

Age: 22+

Code: NCT06928545

Recruiting
Active & Responsive

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

for
Pouchitis
Location: New York NY, Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70+

Code: NCT06312683

Phase 4, Recruiting

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Active & Responsive

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for
Crohn's Disease
Location: London, Halifax, Providence RI, New York NY, Montreal,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT06233461

Phase 2, Recruiting
Active & Responsive

Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

for
Inflammatory Bowel Diseases
Location: Ann Arbor MI
Sponsor: University of Michigan

Sex: All

Age: 18+

Code: NCT06188793

Recruiting
Active & Responsive

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

for
Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer,
Location: Hartford CT, New York NY, Englewood NJ, Florham Park NJ,
Sponsor: VM Oncology, LLC

Sex: All

Age: 18 - 70+

Code: NCT03556228

Phase 1, Phase 2, Recruiting
Active & Responsive

Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC

for
Colorectal Carcinoma Metastatic in the Liver
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT06555133

Phase 2, Recruiting
Active & Responsive

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for
Colorectal Cancer
Location: York PA, Bethesda MD, Goldsboro NC, Canton OH,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05234177

Recruiting
Active & Responsive

Protein Needs Study

for
Colorectal Cancer, Breast Cancer
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 45 - 70+

Code: NCT04144907

Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Boston MA, Providence RI, North Massapequa NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase 3, Recruiting
Active & Responsive

Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)

for
Eosinophilic Esophagitis (EoE)
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 22+

Code: NCT06665971

Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa, Roanoke VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase 1, Phase 2, Recruiting
Active & Responsive

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

for
Gastrointestinal Cancer
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT06065371

Phase 1, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Pennington NJ, Philadelphia PA, Newark DE, Baltimore MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase 1, Phase 2, Recruiting

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

for
Gastrointestinal Symptoms, Digestive Health, Gut Health
Location: San Francisco CA
Sponsor: SF Research Institute, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07421596

Recruiting

Using Virtual Reality for Patients With Gastrointestinal Disease

for
Gastrointestinal Disease, Inflammatory Bowel Diseases
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 8 - 25

Code: NCT03719209

Recruiting

Gastroparesis Registry 4

for
Gastroparesis, Gastroparesis Nondiabetic,
Location: Boston MA, Philadelphia PA, Charlotte NC, Louisville KY,
Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All

Age: 18 - 70+

Code: NCT05846802

Recruiting