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Glioblastoma Clinical Trials

Browse 285 glioblastoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for
High Grade Glioma, CNS Tumor
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 3

Code: NCT06528691

Phase2, Recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252

for
Recurrent High Grade Glioma
Location: New York NY, Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06126744

Phase1, Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for
High Grade Glioma, Diffuse Intrinsic Pontine Glioma
Location: Boston MA, Montreal, Philadelphia PA,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 0 - 21

Code: NCT04655404

Early_phase1, Recruiting

Tumor Treating Fields for the Treatment of Brainstem Gliomas

for
Glioma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT05310448

Recruiting

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

for
Diffuse Intrinsic Pontine Glioma,
Location: Boston MA, Chicago IL, Orange CA
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All

Age: 1 - 18

Code: NCT04943848

Phase1, Recruiting

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A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

for
Bilateral Retinoblastoma, Childhood Intraocular Retinoblastoma,
Location: Montreal, Durham NC, Akron OH, Cleveland OH, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 18

Code: NCT05504291

Phase2, Recruiting

F-Tryptophan PET/CT in Human Cancers

for
Intracranial Glioma, Metastatic Brain Tumor, Breast Cancer,
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT05556473

Phase1, Recruiting

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for
Diffuse Intrinsic Pontine Glioma, DIPG, Brain Tumor, CNS Tumor,
Location: Seattle WA
Sponsor: BrainChild Bio, Inc

Sex: All

Age: 1 - 26

Code: NCT07680439

Phase2, Recruiting

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

for
Glioma
Location: Nashville TN, Orange CA
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT05916313

Phase1, Recruiting

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

for
Neuroblastoma, Diffuse Intrinsic Pontine Glioma
Location: Hershey PA, Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 1 - 30

Code: NCT04837547

Phase1, Recruiting

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for
Recurrent World Health Organization (WHO) Grade II Glioma,
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: University of California, San Francisco

Sex: All

Age: 1 - 25

Code: NCT04485559

Phase1, Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for
Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07628634

Early_phase1, Recruiting

Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)

for
Brain Cancer, HGG, Glioma, High Grade Glioma,
Location: Nashville TN
Sponsor: Eben Rosenthal

Sex: All

Age: 18+

Code: NCT07210632

Early_phase1, Recruiting

A Study of Mirdametinib in People With Central Nervous System Tumors

for
Central Nervous System Tumors, Glioma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07539441

Phase1, Phase2, Recruiting

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

for
Glioma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 3+

Code: NCT07076498

Phase1, Recruiting

Detailed Phenotypic and Genotype Study to Correlate RB1 Mutations Relating to Primary Ocular Tumors and Secondary Extra-ocular Metastasis.

for
Retinoblastoma Bilateral, Retinoblastoma Unilateral,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 0+

Code: NCT06725173

Recruiting

T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas

for
Malignant Glioma
Location: Iowa City IA
Sponsor: John M. Buatti

Sex: All

Age: 21+

Code: NCT07447531

Recruiting

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

for
Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 3 - 39

Code: NCT06914479

Phase1, Recruiting

Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas

for
High-Grade Glioma
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06829173

Early_phase1, Recruiting

Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK

for
Pediatric Low-grade Glioma
Location: Quebec, Sherbrooke, Montreal, Toronto, London, Winnipeg,
Sponsor: St. Justine's Hospital

Sex: All

Age: 2 - 25

Code: NCT06666348

Phase1, Phase2, Recruiting