Glioblastoma Clinical Trials
Find clinical trials for glioblastoma. Search for glioblastoma clinical trials in different cities and states across the United States.
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB TrialA Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
Sponsor:
Duke University
Location:
Code:
NCT06069726
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Atezolizumab
A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
Sponsor:
University of Florida
Location:
Code:
NCT04573140
Conditions
Adult Glioblastoma
High Grade Glioma
WHO Grade III or IV Malignant Glioma
Eligibility Criteria
Sex: All
Age: 4+
Healthy Volunteers: Not accepted
Interventions
Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine administered intravenously (RNA loaded lipid particles, RNA-LPs)
Surgical Pembro +/- Olaparib W TMZ for RGBMSurgical Pembro +/- Olaparib W TMZ for RGBM
Sponsor:
L. Nicolas Gonzalez Castro, MD, PhD
Location:
Code:
NCT05463848
Conditions
Glioblastoma
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Pembrolizumab
Olaparib
Temozolomide
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients with Advanced CancerAt-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients with Advanced Cancer
Sponsor:
Mayo Clinic
Location:
Code:
NCT05969860
Conditions
Advanced Anal Carcinoma
Advanced Biliary Tract Carcinoma
Advanced Bladder Carcinoma
Advanced Breast Carcinoma
Advanced Carcinoid Tumor
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Clinical Encounter
Home Health Encounter
Quality-of-Life Assessment
Questionnaire Administration
A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type GlioblastomaA Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma
Sponsor:
Eudocia Quant Lee, MD
Location:
Code:
NCT06552260
Conditions
Glioblastoma
Recurrent Glioblastoma
Brain Tumor
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Troriluzole
Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®
Sponsor:
Photolitec LLC
Location:
Code:
NCT05363826
Conditions
Glioblastoma Multiforme of Brain
Glioma, Sarcomatous
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
photochemotherapy using 3-(1-Butyloxy)ethyl-3-deacetyl-bacteriopurpurin-18-n-butylimide methyl ester(Photobac®)
Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasChemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT04623931
Conditions
Anaplastic Astrocytoma, IDH-Wildtype
Anaplastic Oligoastrocytoma
Anaplastic Oligodendroglioma
Diffuse Astrocytoma, IDH-Wildtype
Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Quality-of-Life Assessment
Questionnaire Administration
Radiation Therapy
Temozolomide
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
Sponsor:
University of Maryland, Baltimore
Location:
Code:
NCT04699773
Conditions
Glioma
Glioblastoma
Brain Tumor
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
LITT
Hypofractionated Radiation Therapy
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistrySYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Sponsor:
Massive Bio, Inc.
Location:
Code:
NCT03452774
Conditions
Cancer, Metastatic
Cancer
Cancer of Pancreas
Cancer of Liver
Cancer of Stomach
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
Clinical Trial Matching
Study of Olutasidenib and Temozolomide in HGGStudy of Olutasidenib and Temozolomide in HGG
Sponsor:
Rigel Pharmaceuticals
Location:
Code:
NCT06161974
Conditions
High Grade Glioma
Astrocytoma
Astrocytoma, Grade III
Astrocytoma, Grade IV
Diffuse Intrinsic Pontine Glioma
Eligibility Criteria
Sex: All
Age: 12 - 39
Healthy Volunteers: Not accepted
Interventions
Olutasidenib + TMZ