Find clinical trials for Kidney Disease. Search for Kidney Disease clinical trials in different cities and states across the United States.
Sponsor:
Seattle Children's Hospital
Location:
Code:
NCT03618381
Conditions
Pediatric Solid Tumor
Germ Cell Tumor
Retinoblastoma
Hepatoblastoma
Wilms Tumor
Eligibility Criteria
Sex: All
Age: 1 - 30
Healthy Volunteers: Not accepted
Interventions
second generation 4-1BBζ EGFR806-EGFRt
second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG
Sponsor:
University of Michigan
Location:
Code:
NCT05866081
Conditions
Stone, Kidney
Stone Ureter
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Standard of care stent placement
No stent placement
Surveys
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT04557462
Conditions
Primary IgA Nephropathy
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
LNP023
Sponsor:
BicycleTx Limited
Location:
Code:
NCT04561362
Conditions
Urinary Bladder Neoplasm
Triple Negative Breast Neoplasms
Hormone Receptor Positive, HER2-negative Neoplasms
Hormone Receptor Positive, HER2-low Neoplasms
Breast Neoplasms
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
BT8009
Pembrolizumab
Sponsor:
National Center for Research Resources (NCRR)
Location:
Code:
NCT00006331
Conditions
Diabetes Mellitus
Kidney Failure
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
renal transplant
Sponsor:
University of Texas Southwestern Medical Center
Location:
Code:
NCT04759274
Conditions
Edema
Hypervolemia
Chronic Kidney Diseases
Nephrotic Syndrome
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Diuretic Tuner
Sponsor:
University of Alberta
Location:
Code:
NCT05527574
Conditions
Diabetes Type 2
Frailty
Kidney Diseases
Eligibility Criteria
Sex: All
Age: 50 - 70+
Healthy Volunteers: Not accepted
Interventions
Resistance Exercise
Sponsor:
Artiva Biotherapeutics, Inc.
Location:
Code:
NCT06265220
Conditions
Lupus Nephritis - WHO Class III
Lupus Nephritis - WHO Class IV
Refractory Systemic Lupus Erythematosus
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
AB-101
Cyclophosphamide
Fludarabine
Rituximab
Obinutuzumab
Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Location:
Code:
NCT06190626
Conditions
Zellweger Spectrum Disorder
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Sponsor:
Azienda Ospedaliero-Universitaria Careggi
Location:
Code:
NCT05363657
Conditions
Kidney Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Partial Nephrectomy (PN)
Radical Nephrectomy (RN)
Ablation therapy (AT)
Active Surveillance (AS)
Clinical trials for kidney disease are research studies designed to test new treatments, interventions, or diagnostic methods aimed at improving the management and outcomes of kidney conditions including kidney disease. These trials may involve experimental medications, innovative therapies, surgical techniques, or lifestyle interventions.
Kidney disease clinical trials are crucial because they help advance our understanding of kidney disorders so that more effective treatments can be developed. These trials test new drugs, therapies, and diagnostic methods, aiming to improve patient outcomes, slow disease progression, and enhance quality of life.
Clinical trials for kidney disease also provide valuable data on the safety and efficacy of new interventions, which can lead to better management strategies and potential cures. Without clinical trials, the development of innovative solutions and improvements in care for kidney disease would be limited, potentially leaving patients with fewer options and suboptimal outcomes.
Clinical trials for kidney disease can take on many different forms. Researchers will choose the method that best suits the objectives and expected outcomes of the research.
Prevention trials are designed to identify and test strategies that can prevent the onset of kidney disease in high-risk individuals, or slow its progression in those already affected. These trials typically involve interventions like lifestyle changes, new medications, dietary modifications, or supplements that may reduce the risk factors associated with kidney disease, like high blood pressure, diabetes, or obesity.
Participants in prevention trials might include people with a family history of kidney disease, those with chronic conditions known to affect kidney function, or individuals with early signs of kidney damage. The goal is to determine whether the intervention can effectively prevent kidney disease or delay its onset or progression, ultimately reducing the incidence and impact of kidney-related health issues.
Treatment trials in clinical research for kidney disease are designed to evaluate the safety and effectiveness of new therapies or interventions aimed at treating the disease or its complications. These trials often focus on medications, surgical procedures, medical devices, or alternative therapies that could improve kidney function, slow disease progression, or alleviate symptoms.
Participants in treatment trials usually include individuals who have been diagnosed with kidney disease, ranging from early-stage chronic kidney disease (CKD) to more advanced stages, including those requiring dialysis or awaiting a kidney transplant. Treatment trials can also involve comparing the new treatment against standard care or a placebo to determine if it offers superior outcomes.
Quality of life (QoL) trials in kidney disease research focus on understanding and improving the overall well-being and daily functioning of patients living with the condition. These trials assess how treatments, interventions, or disease management strategies affect patients' physical, emotional, and social health.
Participants in QoL trials may include individuals at various stages of kidney disease, including those undergoing dialysis, post-transplant patients, or those managing chronic kidney disease (CKD) with medication. The interventions studied might include new therapies, psychological support programs, dietary changes, or exercise regimens.
Participating in a clinical trial for kidney disease gives participants the opportunity to contribute to scientific research that could benefit wider society. While there are risks and considerations involved, kidney disease clinical trial participation can also offer participants a number of benefits.
Access to cutting-edge treatments, close medical monitoring, and the opportunity to contribute to medical research that may benefit future patients are some of the key benefits of participating in a kidney disease clinical trial. Participants will receive treatment at no cost, gain additional support, and may even experience improved health outcomes. Involvement in a trial for kidney disease also allows patients to take an active role in their healthcare decisions.
Participating in a clinical trial for kidney disease carries risks and considerations, such as the possibility of experiencing side effects from the experimental treatment, which may be unknown or more severe than currently available therapies. There's also the chance that the treatment may not be effective, potentially leading to no improvement or worsening of the condition.
Participants may need to commit significant time for frequent medical visits and tests, and they might have to follow strict trial protocols, which can affect their daily life. Additionally, not all trial-related expenses may be covered, and there's the emotional toll of uncertainty about the trial's outcome.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
Eligibility for participating in a clinical trial for kidney disease varies depending on the specific study, but generally, individuals with a diagnosed kidney condition or those at high risk of developing one may qualify. Trials may target patients at different stages of kidney disease, from early chronic kidney disease (CKD) to those on dialysis or post-transplant.
For most trials, eligibility criteria often include factors like age, gender, medical history, current health status, and previous treatments. Some trials also seek healthy volunteers for comparison.
When participating in a clinical trial for kidney disease, participants can expect to undergo a thorough screening process to ensure they meet the trial’s specific inclusion and exclusion criteria. Following this, a detailed informed consent will be provided where the study’s purpose, procedures, risks, and benefits are explained.
During the trial, participants may receive an experimental treatment, placebo, or standard care, with regular monitoring through medical visits, tests, and assessments to track health and the treatment’s effects.
Enrolling in a clinical trial studying kidney disease through our platform is a straightforward and user-friendly process. Here's how to get started: