A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
for
Advanced Liver Cancers
Location: New Haven CT, Washington D.C. DC, Lexington KY,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT04524871
Phase1, Phase2, Recruiting
Active & Responsive
Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)
for
Hepatocellular Carcinoma
Location: Pittsburgh PA
Sponsor: Anwaar Saeed
Sex: All
Age: 18+
Code: NCT06698250
Phase2, Recruiting
Active & Responsive
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
for
Metastatic Hepatocellular Carcinoma,
Location: New York NY, Pittsburgh PA, Nashville TN
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT06427941
Phase1, Recruiting
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Active & Responsive
DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma
for
Fibrolamellar Hepatocellular Carcinoma (FLC)
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sex: All
Age: 12+
Code: NCT04248569
Phase1, Recruiting
Active & Responsive
DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)
for
Fibrolamellar Hepatocellular Carcinoma
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sex: All
Age: 12+
Code: NCT06027086
Phase1, Phase2, Recruiting
Active & Responsive
Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma
for
Advanced Unresectable Hepatocellular Carcinoma
Location: Baltimore MD, Nashville TN, Fort Worth TX
Sponsor: Riboscience, LLC.
Sex: All
Age: 18+
Code: NCT07175441
Phase2, Recruiting
Active & Responsive
Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
for
Metastatic Melanoma, Liver Metastases
Location: Madison WI
Sponsor: University of Wisconsin, Madison
Sex: All
Age: 18+
Code: NCT07281924
Phase1, Phase2, Recruiting
Active & Responsive
A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function