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Liver Cancer Clinical Trials

Browse 274 liver cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Featured

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

for
Hepatocellular Carcinoma, Pancreatic Ductal Adenocarcinoma,
Location: San Antonio TX
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06084481

Phase1, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: New York NY, Philadelphia PA, Nashville TN, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase1, Recruiting
Active & Responsive

Biobank for Cholestatic Liver Diseases.

for
Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT03445585

Recruiting
Active & ResponsiveNew

CREO - Microwave Ablation Feasibility Study

for
Pancreatic Cancer,
Location: Gilbert AZ
Sponsor: Banner Health

Sex: All

Age: 18+

Code: NCT07817147

Recruiting
Active & Responsive

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for
Metastatic Hepatocellular Carcinoma,
Location: New York NY, Pittsburgh PA, Birmingham AL, Nashville TN,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06427941

Phase1, Phase2, Recruiting

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Active & Responsive

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

for
Hepatocellular Carcinoma
Location: Pittsburgh PA
Sponsor: Anwaar Saeed

Sex: All

Age: 18+

Code: NCT06698250

Phase2, Recruiting
Active & Responsive

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

for
Fibrolamellar Hepatocellular Carcinoma (FLC)
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 12+

Code: NCT04248569

Phase1, Recruiting
Active & Responsive

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

for
Fibrolamellar Hepatocellular Carcinoma
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 12+

Code: NCT06027086

Phase1, Phase2, Recruiting
Active & Responsive

Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma

for
Advanced Unresectable Hepatocellular Carcinoma
Location: Baltimore MD, Nashville TN, Dallas TX, Fort Worth TX
Sponsor: Riboscience, LLC.

Sex: All

Age: 18+

Code: NCT07175441

Phase2, Recruiting
Active & Responsive

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

for
Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma,
Location: Scottsdale AZ
Sponsor: VM Discovery, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07636785

Phase1, Phase2, Recruiting
Active & Responsive

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for
Unresectable or Metastatic Hepatocellular Carcinoma,
Location: Boston MA, Atlanta GA, Peoria IL, Orange CA, Irvine CA,
Sponsor: CatalYm GmbH

Sex: All

Age: 18 - 70+

Code: NCT07219459

Phase2, Recruiting
Active & Responsive

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

for
Metastatic Melanoma, Liver Metastases
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT07281924

Phase1, Phase2, Recruiting
Active & Responsive

Personalized Neoantigen Vaccine Plus IL-12 (INO-9012) Versus Active Surveillance in Subjects With High-Risk HCC

for
HCC
Location: New York NY, Baltimore MD, New Orleans LA
Sponsor: Geneos Therapeutics

Sex: All

Age: 18+

Code: NCT07722741

Phase2, Recruiting
Active & Responsive

Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis

for
Colorectal Adenocarcinoma Metastatic in the Liver,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07764497

Phase2, Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Scarborough ME, Worcester MA, Hartford CT, Norwalk CT,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC

for
Colorectal Carcinoma Metastatic in the Liver
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT06555133

Phase2, Recruiting
Active & Responsive

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

for
Uveal Melanoma, Cutaneous Melanoma, BAP1 Gene Mutation,
Location: Columbus OH
Sponsor: Mohamed Abdel-Rahman

Sex: All

Age: 0+

Code: NCT04792463

Recruiting
New

A Study Evaluating a New Radiation Treatment Workflow (NGDS)

for
Lung Cancer (Diagnosis), Liver Cancer, Adult, Pancreatic Cancer,
Location: Cleveland OH, St Louis MO
Sponsor: Varian, a Siemens Healthineers Company

Sex: All

Age: 21+

Code: NCT07824583

Recruiting
New

Protoacoustic Imaging For 3D Mapping

for
Proton Therapy, Radiation Therapy, Secondary Skin Reactions,
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 18+

Code: NCT07832617

Recruiting