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Ophthalmology Clinical Trials

Browse 807 Ophthalmology clinical trials enrolling across the United States and Canada. 92 people applied to Ophthalmology studies last month. Search by city or state to find one near you.

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Active & Responsive

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

for
Multiple Sclerosis, Clinically Isolated Syndrome, NMOSD,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: Female

Age: 18 - 64

Code: NCT06940323

Recruiting
Active & Responsive

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking

for
Keratoconus, Unstable, Bacterial Keratitis, Ectasia of Cornea
Location: Eugene OR
Sponsor: Pacific Clear Vision Institute

Sex: All

Age: 12 - 45

Code: NCT03918408

Phase 1, Recruiting
Active & Responsive

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for
Geographic Atrophy
Location: Philadelphia PA, Baltimore MD, Durham NC, Lynchburg VA,
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT05626114

Phase 2, Recruiting
Active & Responsive

Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm

for
Benign Essential Blepharospasm, Hemifacial Spasm
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 18+

Code: NCT06195241

Recruiting
Active & Responsive

Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal Ectasia

for
Keratoconus, Corneal Ectasia
Location: Teaneck NJ
Sponsor: Cornea and Laser Eye Institute

Sex: All

Age: 12+

Code: NCT04905108

Phase 3, Recruiting

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Active & Responsive

Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A Light

for
Keratoconus, Corneal Ectasia
Location: Teaneck NJ
Sponsor: Cornea and Laser Eye Institute

Sex: All

Age: 18+

Code: NCT05027295

Phase 3, Recruiting
Active & Responsive

Ocular Blood Flow Imaging for Glaucoma Assessment

for
Glaucoma
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18 - 70+

Code: NCT05726058

Recruiting
Active & Responsive

Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose

for
Keratoconus, Corneal Ectasia
Location: Teaneck NJ
Sponsor: Cornea and Laser Eye Institute

Sex: All

Age: 12+

Code: NCT04897503

Phase 3, Recruiting
Active & Responsive

Wavelength Intervention for Nearsighted Kids

for
Myopia
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 7 - 12

Code: NCT06598423

Recruiting
Active & Responsive

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

for
Uveal Melanoma, Cutaneous Melanoma, BAP1 Gene Mutation,
Location: Columbus OH
Sponsor: Mohamed Abdel-Rahman

Sex: All

Age: 0+

Code: NCT04792463

Recruiting
Active & Responsive

Vasculitis Pregnancy Registry

for
Vasculitis, Behcet's Disease, CNS Vasculitis,
Location: Tampa FL
Sponsor: University of Pennsylvania

Sex: Female

Age: 18 - 50

Code: NCT02593565

Recruiting
Active & Responsive

Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)

for
Center Involved Diabetic Macular Edema, Diabetic Macular Edema
Location: Deerfield Beach FL, Erie PA, La Crosse WI, Bellaire TX,
Sponsor: Ocugen

Sex: All

Age: 18+

Code: NCT05802329

Phase 1, Recruiting
Active & Responsive

Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)

for
Stargardt Disease, Stargardt Disease 1, Cone Rod Dystrophy,
Location: Boston MA, Gainesville FL, Ann Arbor MI, Cincinnati OH,
Sponsor: Ascidian Therapeutics, Inc

Sex: All

Age: 5+

Code: NCT06445322

Recruiting
Active & Responsive

OCT Angiography in Wet AMD

for
Neovascular (Wet) Age-related Macular Degeneration (AMD)
Location: Portland OR
Sponsor: Oregon Health and Science University

Sex: All

Age: 50 - 70+

Code: NCT02253030

Recruiting
Active & Responsive

Effects of Goji vs. Fiber on Macular Degeneration

for
Age-Related Macular Degeneration
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 65 - 70+

Code: NCT06237127

Recruiting
Active & Responsive

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

for
X-linked Retinoschisis
Location: Boston MA, New York NY, Philadelphia PA, Durham NC,
Sponsor: Atsena Therapeutics Inc.

Sex: All

Age: 5+

Code: NCT05878860

Phase 3, Recruiting
Active & Responsive

Comparative Study of Ziplyft Treatment vs. Traditional Blepharoplasty for Upper Eyelid Rejuvenation

for
Dermatochalasis of Upper Eyelid, Ptosis, Eyelid, Blepharoplasty
Location: Oxford NC
Sponsor: Osheru Inc.

Sex: All

Age: 35+

Code: NCT07250139

Recruiting
Active & Responsive

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

for
Diabetic Retinopathy, Macular Edema
Location: Waterford CT, Greenville NC, Liverpool NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705607

Phase 3, Recruiting
Active & Responsive

Wellness in PSP and CBD

for
Progressive Supranuclear Palsy, Corticobasal Degeneration
Location: Vancouver
Sponsor: Silke Cresswell

Sex: All

Age: 19+

Code: NCT07844655

Recruiting
Active & Responsive

Pivotal Trial for an Automated AI-based System for Detection of Diabetic Retinopathy

for
Diabetic Retinopathy (DR)
Location: Jacksonville FL
Sponsor: Digital Diagnostics, Inc.

Sex: All

Age: 22+

Code: NCT07844317

Recruiting

What are ophthalmology clinical trials?

Ophthalmology clinical trials are research studies designed to evaluate new treatments, therapies, or diagnostic methods for eye diseases and conditions. These trials focus on a wide range of ophthalmic issues, including but not limited to glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, cataracts, and retinal diseases. Clinical trials in ophthalmology may test new medications, surgical techniques, laser treatments, or medical devices to improve vision, prevent blindness, or manage symptoms of eye diseases.

The data collected from these trials helps advance understanding and development of better treatment options, ultimately aiming to enhance eye health and visual outcomes for patients.

Why are clinical trials for ophthalmology important?

With a vast range of eye conditions and diseases falling under the ophthalmology umbrella, clinical research in this area is highly important. Ophthalmology clinical trials are crucial for driving the development of new and more effective treatments for eye diseases and conditions, which can significantly impact vision and quality of life.

Clinical trials for ophthalmology help researchers to evaluate novel medications, surgical techniques, and diagnostic tools, potentially leading to breakthroughs in managing or curing a range of conditions. Ophthalmology clinical trials play a key role in reducing the burden of visual impairment and blindness, enhancing eye health, and promoting better visual outcomes for future patients.

What types of clinical trials are used for ophthalmology?

Participation in an ophthalmology clinical trial

Who can participate in a clinical trial for ophthalmology?

How to enroll in a ophthalmology clinical trial