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Ophthalmology Clinical Trials

Browse 805 Ophthalmology clinical trials enrolling across the United States and Canada. 112 people applied to Ophthalmology studies last month. Search by city or state to find one near you.

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Senofilcon A Lenses in Moderate to Severe Dry Eye Disease

for
Moderate to Severe Dry Eye Disease
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT04096898

Recruiting

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting

for
Corneal Melting in Boston Keratoprosthesis Type I
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18 - 70+

Code: NCT03041883

Recruiting

Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)

for
Smith-Lemli-Opitz Syndrome, Cone-Rod Dystrophy, Hearing Loss
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 0 - 65

Code: NCT01773278

Phase 2, Recruiting

Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' Dystrophy

for
Fuchs Endothelial Dystrophy
Location: Portland OR
Sponsor: Michael D. Straiko, MD

Sex: All

Age: 30 - 70+

Code: NCT03813056

Phase 2, Recruiting

Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC

for
Cataract
Location: Venice FL, Racine WI
Sponsor: Inder Paul Singh, M.D.

Sex: All

Age: 18+

Code: NCT06681688

Phase 1, Phase 2, Recruiting

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Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

for
Stargardt-Like Macular Dystrophy
Location: Bethesda MD
Sponsor: National Eye Institute (NEI)

Sex: All

Age: 10 - 70+

Code: NCT04591483

Recruiting

Optical Coherence Tomography (OCT) in Uveitis

for
Uveitis
Location: Portland OR
Sponsor: Oregon Health and Science University

Sex: All

Age: 18+

Code: NCT02026128

Recruiting

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

for
Xerostomia, Graft-versus-host-disease, Sjogren's Disease
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18 - 70+

Code: NCT06392711

Phase 1, Recruiting

Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

for
Optic Neuritis
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18 - 55

Code: NCT02521311

Phase 2, Recruiting

Duration of Face Down Positioning for Full-Thickness Macular Hole Repair

for
Macular Holes
Location: Stoney Creek
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT06000111

Recruiting

Study of Selected X-Linked Disorders: Aicardi Syndrome

for
Aicardi Syndrome, Brain Disorders
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0+

Code: NCT00697411

Recruiting

Cross Linking Corneal Biomechanical Evaluation of CATS Tonometer Prism

for
Keratoconus
Location: Tucson AZ
Sponsor: Intuor Technologies, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04180111

Recruiting

Biorepository and Registry for Plasma Exchange Patients

for
Antibody-mediated Rejection, NMO Spectrum Disorder, TTP, CIDP
Location: Iowa City IA
Sponsor: Charles M Knudson

Sex: All

Age: 12 - 70+

Code: NCT05004493

Recruiting

Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy

for
Neuromyelitis Optica Spectrum Disorder, Pregnancy Related
Location: Aurora CO
Sponsor: Amgen

Sex: Female

Age: 15+

Code: NCT05909761

Recruiting

Intense Treatment Regimen With Intravitreal Aflibercept Injection

for
Neovascular Age-Related Macular Degeneration
Location: New York NY
Sponsor: Vitreous -Retina- Macula Consultants of New York

Sex: All

Age: 50+

Code: NCT03594461

Phase 1, Phase 2, Recruiting

A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

for
Scleritis
Location: Palisades Park NJ, San Antonio TX, Palo Alto CA
Sponsor: Metropolitan Eye Research & Surgery Institute

Sex: All

Age: 18+

Code: NCT03465111

Phase 2, Recruiting

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

for
Cystoid Macular Edema
Location: Boston MA
Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All

Age: 18 - 70+

Code: NCT04225611

Phase 1, Phase 2, Recruiting

Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated Patients

for
LCA5
Location: Philadelphia PA, Dallas TX
Sponsor: Opus Genetics, Inc

Sex: All

Age: 4+

Code: NCT05616793

Phase 1, Phase 2, Recruiting

Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension

for
Open Angle Glaucoma, Ocular Hypertension
Location: Newport Beach CA
Sponsor: Glaukos Corporation

Sex: All

Age: 18+

Code: NCT06152861

Phase 2, Recruiting

New Pediatric Patching Method to Improve Compliance

for
Amblyopia, Strabismus
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 7

Code: NCT02236351

Recruiting

What are ophthalmology clinical trials?

Ophthalmology clinical trials are research studies designed to evaluate new treatments, therapies, or diagnostic methods for eye diseases and conditions. These trials focus on a wide range of ophthalmic issues, including but not limited to glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, cataracts, and retinal diseases. Clinical trials in ophthalmology may test new medications, surgical techniques, laser treatments, or medical devices to improve vision, prevent blindness, or manage symptoms of eye diseases.

The data collected from these trials helps advance understanding and development of better treatment options, ultimately aiming to enhance eye health and visual outcomes for patients.

Why are clinical trials for ophthalmology important?

With a vast range of eye conditions and diseases falling under the ophthalmology umbrella, clinical research in this area is highly important. Ophthalmology clinical trials are crucial for driving the development of new and more effective treatments for eye diseases and conditions, which can significantly impact vision and quality of life.

Clinical trials for ophthalmology help researchers to evaluate novel medications, surgical techniques, and diagnostic tools, potentially leading to breakthroughs in managing or curing a range of conditions. Ophthalmology clinical trials play a key role in reducing the burden of visual impairment and blindness, enhancing eye health, and promoting better visual outcomes for future patients.

What types of clinical trials are used for ophthalmology?

Participation in an ophthalmology clinical trial

Who can participate in a clinical trial for ophthalmology?

How to enroll in a ophthalmology clinical trial