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Sarcoma Clinical Trials

Browse 918 sarcoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor

for
Gastrointestinal Stromal Tumors
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT07171203

Phase1, Recruiting

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

for
KRAS-mutant Non-small Cell Lung Cancer (NSCLC),
Location: Boston MA, Philadelphia PA, Fairfax VA, Tampa FL,
Sponsor: Kestrel Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07458347

Phase1, Recruiting

A Phase 1 Study of D3S-003 as Monotherapy in Participants With Advanced Solid Tumors With a KRAS p.G12D Mutation.

for
KRAS P.G12D
Location: New Haven CT, Houston TX, San Antonio TX
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT07456046

Phase1, Recruiting

DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical Margins

for
Neurofibromas, MPNST
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 1+

Code: NCT07298083

Recruiting

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

for
Hodgkin Disease, CD30-Positive Diffuse Large B-Cell Lymphoma,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT05544968

Phase1, Recruiting

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Venetoclax Basket Trial for High Risk Hematologic Malignancies

for
Myelodysplastic Syndromes, de Novo,
Location: Boston MA, Atlanta GA, Chicago IL, Aurora CO,
Sponsor: Andrew E. Place, MD

Sex: All

Age: 1 - 40

Code: NCT05292664

Phase1, Recruiting

Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for
Lymphoma Diffuse Large B-cell, Leukemia and Lymphoma,
Location: Nashville TN
Sponsor: AvenCell Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07284433

Phase1, Phase2, Recruiting

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for
Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia
Location: Burlington MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04840602

Phase2, Recruiting

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

for
Leukemia, Lymphoma
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07294677

Phase1, Phase2, Recruiting

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

for
Large B-cell Lymphoma
Location: Ottawa, Calgary
Sponsor: AstraZeneca

Sex: All

Age: 65 - 70+

Code: NCT07215585

Phase3, Recruiting

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

for
Osteosarcoma, Metastasis
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 6 - 49

Code: NCT07477457

Phase2, Recruiting

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Phoenix AZ, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 54

Code: NCT06918431

Phase2, Recruiting

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

for
Lymphoma, Marginal Zone Lymphoma, MZL
Location: Boston MA
Sponsor: Gottfried von Keudell, MD PhD

Sex: All

Age: 18+

Code: NCT06510309

Phase2, Recruiting

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

for
Follicular Lymphoma (FL)
Location: Saint John, Boston MA, Quebec, Stony Brook NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06091254

Phase3, Recruiting

Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07042438

Phase2, Recruiting

SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas

for
Non Hodgkin Lymphoma, Solid Tumor
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT07222631

Phase1, Phase2, Recruiting

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

for
Lymphoma, Lymphoma, Large B-Cell, Diffuse
Location: Boston MA, Miami FL
Sponsor: Jennifer Crombie, MD

Sex: All

Age: 18+

Code: NCT05800366

Phase2, Recruiting

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

for
Hematological Malignancies, B-cell Non-Hodgkin Lymphoma
Location: New York NY
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT07220616

Phase1, Phase2, Recruiting

A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab

for
B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia,
Location: Little Rock AR, Springdale AR
Sponsor: Arkansas Children's Hospital Research Institute

Sex: All

Age: 1 - 23

Code: NCT07422337

Recruiting

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

for
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07224100

Phase2, Recruiting