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Sarcoma Clinical Trials

Browse 918 sarcoma clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

for
Mature B-Cell Non-Hodgkin Lymphoma
Location: Boston MA, New York NY, Baltimore MD, Cincinnati OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 30

Code: NCT05533775

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: New Haven CT, Stony Brook NY, New Brunswick NJ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase3, Recruiting
Featured

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Location: Columbus OH, Rochester MN, Salt Lake City UT
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05091424

Phase1, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Rimouski, Boston MA, Worcester MA, Hartford CT, Quebec,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase3, Recruiting
Featured

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Boston MA, Albany NY, Virginia Beach VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06806033

Phase2, Recruiting

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Featured

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

for
Diffuse Large B-cell Lymphoma, Follicular Lymphoma
Location: St. John's, Moncton, Kingston, Greater Sudbury,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06830759

Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

for
Neoplasms
Location: New Haven CT, Toronto, Sarasota FL, Houston TX,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06884618

Phase1, Recruiting
Active & Responsive

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

for
Metastatic Sarcoma, Recurrent Sarcoma, Resectable Sarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 10+

Code: NCT04199026

Recruiting
Active & Responsive

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for
Metastatic Dedifferentiated Liposarcoma,
Location: Boston MA, Waterford CT, Guilford CT, New Haven CT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06422806

Phase3, Recruiting
Active & ResponsiveNew

Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention

for
Sarcoma, Bone Sarcoma, Soft Tissue Sarcoma (STS)
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 15 - 39

Code: NCT07662239

Recruiting
Active & Responsive

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

for
Neuroblastoma, Sarcoma
Location: The Bronx NY, Washington D.C. DC, Columbus OH,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 40

Code: NCT05135975

Phase2, Recruiting
Active & Responsive

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for
Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma,
Location: Boston MA, New York NY, Baltimore MD,
Sponsor: Carl Allen

Sex: All

Age: 0+

Code: NCT04079179

Phase2, Recruiting
Active & Responsive

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

for
Neuroblastoma, Sarcoma, Osteosarcoma
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 2 - 30

Code: NCT06500819

Phase1, Recruiting
Active & Responsive

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 0 - 21

Code: NCT02508038

Phase1, Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for
Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT07514819

Recruiting
Active & Responsive

A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma

for
HLA-A*0201 Positive Cells Present, Clear Cell Sarcoma (CCS)
Location: New York NY, Los Angeles CA
Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All

Age: 18+

Code: NCT06942442

Phase2, Recruiting
Active & Responsive

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for
Neuroblastoma, Rhabdomyosarcoma, Synovial Sarcoma,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 25

Code: NCT06625190

Phase1, Phase2, Recruiting
Active & Responsive

Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma

for
Osteogenic Sarcoma Recurrent
Location: Hackensack NJ, Houston TX
Sponsor: Hackensack Meridian Health

Sex: All

Age: 8 - 30

Code: NCT05726383

Phase2, Recruiting
Active & Responsive

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

for
Locally Advanced Clear Cell Renal Cell Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT06866262

Phase1, Phase2, Recruiting