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Bristol Myers Squibb Clinical Trials

Find clinical trials for Bristol Myers Squibb. Search for Bristol Myers Squibb clinical trials in different cities and states across the United States.

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Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for
Alzheimer's Disease
Location: Halifax, East Providence RI, Newton MA, Quebec,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976216

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Effect of KarXT on Urological Safety

for
Schizophrenia
Location: Marlton NJ, Philadelphia PA, West Palm Beach FL,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07221877

Recruiting
Active & Responsive

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for
Alzheimer Disease
Location: North Dartmouth MA, Boston MA, Belmont MA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06585787

Phase 3, Recruiting
Active & Responsive

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

for
Bipolar Disorder Type I With Mania
Location: New Haven CT, Staten Island NY, Marlton NJ,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT06929273

Phase 3, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for
Mania, Bipolar Disorder
Location: Staten Island NY, Hallandale FL, West Palm Beach FL,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07140913

Phase 3, Recruiting

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Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

for
Bipolar-I Disorder With Mania or Mania With Mixed Features
Location: New Haven CT, Staten Island NY, West Palm Beach FL,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT06951698

Phase 3, Recruiting
Active & Responsive

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

for
Schizophrenia
Location: Philadelphia PA, Wilmington NC, Cary NC, Miami FL,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07379827

Recruiting
Active & Responsive

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

for
Anemia, Sickle Cell, Healthy Volunteers
Location: Boston MA, New Haven CT, Philadelphia PA, Richmond VA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06481306

Phase 1, Phase 2, Recruiting
Active & ResponsiveNew

A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function

for
Kidney Failure, Chronic
Location: Miami Lakes FL, Orlando FL, Chandler AZ
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 70+

Code: NCT07763418

Phase 1, Recruiting
Active & Responsive

A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Locally Advanced Non-Small Cell Lung Cancer (NSCLC),
Location: Athens GA, Omaha NE, Grand Island NE
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07680764

Phase 2, Recruiting
Active & Responsive

A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

for
Arthritis, Rheumatoid
Location: Denver CO
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07412704

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for
Solid Tumors
Location: New York NY, Baltimore MD, Atlanta GA, Houston TX
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07492680

Phase 2, Recruiting
New

Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)

for
Non-Small Cell Lung Cancer
Location: Winchester VA, Palm Bay FL, Beaumont TX, San Antonio TX
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07680790

Phase 3, Recruiting
New

A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants

for
Healthy Female Adults
Location: Quebec
Sponsor: Bristol-Myers Squibb

Sex: Female

Age: 18 - 55

Code: NCT07800897

Phase 1, Recruiting
New

Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy Volunteers

for
Healthy Volunteers
Location: Hollywood FL, Decatur GA, Atlanta GA, Los Alamitos CA
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 18 - 65

Code: NCT07681076

Phase 4, Recruiting
New

A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration

for
Alzheimer's Disease, Healthy Participants
Location: Anaheim CA
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 70+

Code: NCT07780383

Phase 1, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase 1, Phase 2, Recruiting

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

for
Multiple Sclerosis, Relapsing-Remitting
Location: Tampa FL, Louisville KY, Chicago IL, Milwaukee WI,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 10 - 17

Code: NCT06408259

Phase 3, Recruiting

A Study of Patients With Relapsed/Refractory Mantle Cell Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

for
Mantle Cell Lymphoma (MCL)
Location: Milwaukee WI
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06788652

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for
Lung Cancer, Breast Cancer
Location: Hackensack NJ, Montreal, Ottawa, Miami FL, Cleveland OH,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06618287

Phase 1, Phase 2, Recruiting