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Roche Clinical Trials

Find clinical trials for Roche. Search for Roche clinical trials in different cities and states across the United States.

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A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

for
Muscular Atrophy, Spinal
Location: Philadelphia PA, Gainesville FL, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 2

Code: NCT05861999

Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for
Moderately to Severely Active Ulcerative Colitis
Location: Providence RI, Lebanon NH, North Massapequa NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06588855

Phase3, Recruiting
FeaturedActive & Responsive

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

for
Influenza
Location: Miami FL, Charleston SC, Smithfield PA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 11

Code: NCT06094010

Phase3, Recruiting
FeaturedActive & Responsive

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for
Metastatic Colorectal Cancer
Location: Port Jefferson Station NY, New Haven CT,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT04929223

Phase1, Recruiting
FeaturedActive & Responsive

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for
Metastatic Breast Cancer
Location: Durham NC, Chattanooga TN, Nashville TN, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT03424005

Phase1, Phase2, Recruiting

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FeaturedActive & Responsive

A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis

for
Multiple Sclerosis
Location: Montreal
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 65

Code: NCT05704361

Phase1, Recruiting
FeaturedActive & Responsive

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

for
Neuromyelitis Optica Spectrum Disorder, NMOSD
Location: Denver CO
Sponsor: Hoffmann-La Roche

Sex: All

Age: 2 - 11

Code: NCT05199688

Phase3, Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Boston MA, Providence RI, North Massapequa NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase3, Recruiting
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A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

for
Mature B-Cell Non-Hodgkin Lymphoma
Location: Boston MA, New York NY, Baltimore MD, Cincinnati OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0 - 30

Code: NCT05533775

Phase1, Phase2, Recruiting
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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Boston MA, Philadelphia PA, Charlotte NC, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase1, Phase2, Recruiting