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Paid Clinical Trials Costa Mesa

Discover 3,561 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Cannabidiol in Sanfilippo Syndrome

for
Sanfilippo Syndrome, Mucopolysaccharidosis III
Location: Torrance CA
Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Sex: All

Age: 4+

Code: NCT06333041

Phase2, Phase3, Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants.

for
Healthy
Location: Glendale CA
Sponsor: AstraZeneca

Sex: All

Age: 18 - 50

Code: NCT06995820

Phase1, Recruiting

Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Torrance CA, Monterey CA, Walnut Creek CA,
Sponsor: N-Power Medicine

Sex: All

Age: 18+

Code: NCT07028489

Recruiting

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

for
Parkinson Disease
Location: Los Alamitos CA, Austin TX, Farmington Hills MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 30 - 70+

Code: NCT06809400

Phase1, Recruiting

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

for
Breast Cancer
Location: Fullerton CA, Los Angeles CA, Billings MT, Seattle WA,
Sponsor: Celcuity Inc

Sex: All

Age: 18+

Code: NCT06757634

Phase3, Recruiting

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A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for
Metastatic Gastric Adenocarcinoma,
Location: Los Alamitos CA, Las Vegas NV, Chandler AZ,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07043400

Phase3, Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

for
Refractory Metastatic Colorectal Cancer
Location: Duarte CA, Santa Monica CA, Salt Lake City UT,
Sponsor: Delcath Systems Inc.

Sex: All

Age: 18+

Code: NCT06607458

Phase2, Recruiting

Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06860815

Phase2, Recruiting

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

for
HER2-positive Breast Cancer, Breast Cancer
Location: Los Alamitos CA, Long Beach CA, Albuquerque NM,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07102381

Phase2, Recruiting

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

for
COVID-19, SARS-CoV-2 Infection
Location: Los Angeles CA, San Francisco CA
Sponsor: Kara Chew

Sex: All

Age: 40 - 64

Code: NCT06810934

Phase1, Phase2, Recruiting

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

for
Prostate Cancer
Location: Los Angeles CA, Santa Monica CA, Santa Barbara CA,
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18 - 70+

Code: NCT06780670

Phase2, Phase3, Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for
Breast Neoplasms
Location: Los Alamitos CA, Los Angeles CA, Santa Monica CA,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07173751

Phase3, Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Duarte CA, Los Angeles CA, West Valley City UT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06465069

Phase1, Recruiting

High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy

for
Diabetic Macular Edema (DME)
Location: Fullerton CA
Sponsor: Retina Consultants of Orange County

Sex: All

Age: 21+

Code: NCT06662994

Recruiting

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for
Sickle Cell Trait
Location: Loma Linda CA, Houston TX, Birmingham AL,
Sponsor: National Alliance for Sickle Cell Centers

Sex: All

Age: 18+

Code: NCT06071377

Recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for
Invasive Mold Infections
Location: Duarte CA, Los Angeles CA, Sacramento CA, Vancouver,
Sponsor: Basilea Pharmaceutica

Sex: All

Age: 18+

Code: NCT06925321

Phase3, Recruiting

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for
T-cell Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Duarte CA, Los Angeles CA, Denver CO, Seattle WA,
Sponsor: Allotera Therapeutics

Sex: All

Age: 0+

Code: NCT06514794

Phase2, Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for
Colorectal Neoplasms
Location: Los Alamitos CA, Torrance CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06750094

Phase3, Recruiting

The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement

for
Dementia
Location: Los Angeles CA
Sponsor: Healthy Minds Initiative

Sex: All

Age: 55 - 70+

Code: NCT06741865

Recruiting

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for
Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation,
Location: Los Alamitos CA, Los Angeles CA, Houston TX, Chicago IL,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT06501625

Phase1, Phase2, Recruiting