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Paid Clinical Trials Costa Mesa

Discover 3,605 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Burbank CA, Phoenix AZ, Reno NV, Grand Junction CO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06170788

Phase 3, Recruiting

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for
T-Cell Neoplasm, Lymphoproliferative Disorders
Location: Duarte CA, Ann Arbor MI, Columbus OH, Durham NC
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT04858256

Phase 2, Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

for
Hypogammaglobulinemia, Bacterial Infections,
Location: Huntington Park CA, Bullhead City AZ, Canton OH,
Sponsor: Grifols Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05645107

Phase 3, Recruiting

Study of ALTO-300 in MDD

for
Major Depressive Disorder
Location: Bellflower CA, Temecula CA, Moorpark CA, Las Vegas NV,
Sponsor: Alto Neuroscience

Sex: All

Age: 18 - 70

Code: NCT05922878

Phase 2, Recruiting

Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer

for
Early-stage Breast Cancer, Breast Carcinoma in Situ,
Location: Santa Monica CA
Sponsor: Saint John's Cancer Institute

Sex: All

Age: 18+

Code: NCT04603209

Recruiting

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A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Los Angeles CA, Dallas TX, Houston TX, Ann Arbor MI,
Sponsor: LigaChem Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05941507

Phase 1, Phase 2, Recruiting

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for
Ovarian Cancer
Location: Burbank CA, La Jolla CA, Palo Alto CA,
Sponsor: Daiichi Sankyo

Sex: Female

Age: 18+

Code: NCT06819007

Phase 3, Recruiting

Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections

for
Necrotizing Soft Tissue Infection
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06002607

Recruiting

Study of ATX-01 in Participants With DM1

for
Myotonic Dystrophy 1
Location: Los Angeles CA, Fairway KS, Iowa City IA,
Sponsor: ARTHEx Biotech S.L.

Sex: All

Age: 18 - 64

Code: NCT06300307

Phase 1, Phase 2, Recruiting

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

for
Breast Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 18+

Code: NCT06171607

Phase 1, Recruiting

The Actuate-CBC Study

for
Telemedicine
Location: Orange CA, Saint Paul MN, Ann Arbor MI
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT05917652

Recruiting

An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib

for
Ovary Cancer, Peritoneal Cancer, Fallopian Tube Cancer
Location: Irvine CA, Aurora CO, Madison WI, Chicago IL,
Sponsor: University of Colorado, Denver

Sex: Female

Age: 18 - 70+

Code: NCT05887609

Phase 2, Recruiting

Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

for
Solid Tumor, Adult, Oncology
Location: Santa Monica CA, Huntersville NC
Sponsor: Trethera

Sex: All

Age: 18+

Code: NCT05055609

Phase 1, Recruiting

Aspirin for Postpartum Patients With Preeclampsia

for
Preeclampsia Postpartum
Location: Long Beach CA
Sponsor: MemorialCare Health System

Sex: Female

Age: 18+

Code: NCT05924971

Phase 2, Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for
Heart Failure, Left Ventricular Systolic Dysfunction
Location: Los Angeles CA, San Bernardino CA, Palo Alto CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT05714085

Phase 2, Phase 3, Recruiting

Intraoperative Electrically-evoked ABRs in Patients Undergoing Vestibular Schwannoma Surgery

for
Deafness
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT05248113

Recruiting

Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)

for
Critical Limb Ischemia
Location: Los Angeles CA
Sponsor: Leonardo Clavijo

Sex: All

Age: 40 - 70+

Code: NCT04306471

Recruiting

Aveir DR Real-World Evidence Post-Approval Study

for
Cardiac Pacemaker, Arrythmia, Bradycardia
Location: Sylmar CA
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT05935007

Recruiting

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

for
Renal Pelvis and Ureter Urothelial Carcinoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05775471

Phase 2, Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for
Acute Respiratory Distress Syndrome (ARDS), ARDS,
Location: Orange CA, Long Beach CA, Fresno CA, Stanford CA,
Sponsor: PPD Development, LP

Sex: All

Age: 18+

Code: NCT06701656

Phase 2, Recruiting