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Paid Clinical Trials Costa Mesa

Discover 3,564 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for
Psychosis Associated With Alzheimer's Disease
Location: Anaheim CA, Los Angeles CA, Pasadena CA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT05980949

Phase3, Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Los Angeles CA, Las Vegas NV, Fresno CA, San Jose CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Orange CA, Laguna Hills CA, San Diego CA, Palo Alto CA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06943872

Phase3, Recruiting

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

for
Gastroesophageal Adenocarcinoma
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT05733689

Phase1, Recruiting

Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for
Non-small Cell Lung Cancer (NSCLC)
Location: Orange CA, Los Angeles CA, Boise ID, Austin TX,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT07154706

Phase3, Recruiting

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Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder

for
Posttraumatic Stress Disorder
Location: Los Angeles CA
Sponsor: VA Greater Los Angeles Healthcare System

Sex: Male

Age: 25 - 70

Code: NCT02091843

Recruiting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

for
Ulcerative Colitis, Ulcerative Colitis Chronic
Location: Orange CA, Garden Grove CA, Los Alamitos CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06598943

Phase2, Recruiting

Impact of Ranolazine on Myocardial Ischemia Detected by High-Field 3T Cardiovascular Magnetic Resonance (CMR) Imaging and P-31 Spectroscopy

for
Angina, Heart Disease
Location: Beverly Hills CA
Sponsor: Westside Medical Associates of Los Angeles

Sex: All

Age: 18+

Code: NCT01804543

Recruiting

Clinical Study of the inQB8 TTVR System (The MonarQ Study)

for
Tricuspid Valve Regurgitation
Location: Los Angeles CA, Thousand Oaks CA, Plano TX, Atlanta GA,
Sponsor: inQB8 Medical Technologies, LLC

Sex: All

Age: 18+

Code: NCT06611579

Recruiting

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for
Infusion Reactions
Location: Duarte CA, La Jolla CA, San Diego CA, Phoenix AZ,
Sponsor: New York Blood Center

Sex: All

Age: 0+

Code: NCT01656603

Phase2, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Glendale CA, Sacramento CA, Albuquerque NM, El Paso TX,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase3, Recruiting

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

for
Solid Tumor, Adult, Malignant Solid Tumor,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06824363

Early_phase1, Recruiting

Pain and Major Depressive Disorder

for
Major Depressive Disorder, Chronic Pain
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT04556890

Recruiting

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for
Propionic Acidemia
Location: Los Angeles CA, Stanford CA, Houston TX, Edmonton,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 0+

Code: NCT04159103

Phase1, Phase2, Recruiting

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

for
Multiple Myeloma, Secondary Immunodeficiency
Location: Orange CA, Westwood KS, Winnipeg, St Louis MO,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06980480

Phase3, Recruiting

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

for
Cesarean Section Complications, Cesarean Section; Infection
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: Female

Age: 18+

Code: NCT06339203

Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for
B-cell Acute Lymphoblastic Leukemia,
Location: Los Angeles CA, Salt Lake City UT, Aurora CO,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 25

Code: NCT06395103

Phase1, Phase2, Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia
Location: Orange CA, Duarte CA, Palo Alto CA, Salt Lake City UT,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07277231

Phase3, Recruiting

Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer

for
Breast Cancer, Metastatic Breast Cancer,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT05524584

Phase2, Recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

for
Severe Combined Immunodeficiency, X Linked, Gene Therapy
Location: Los Angeles CA, Cincinnati OH, Atlanta GA, Boston MA
Sponsor: David Williams

Sex: Male

Age: 0 - 5

Code: NCT03311503

Phase1, Phase2, Recruiting