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Paid Clinical Trials Costa Mesa

Discover 3,605 paid clinical trials in Costa Mesa, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for
Degenerative Disc Disease
Location: Santa Monica CA, Thousand Oaks CA, Phoenix AZ,
Sponsor: DiscGenics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07254806

Phase 3, Recruiting
Active & Responsive

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for
Knee Cartilage Defects
Location: Santa Monica CA, Encinitas CA, La Jolla CA, La Mesa CA,
Sponsor: Medipost, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07339111

Phase 3, Recruiting
Active & Responsive

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

for
Lumbar Disc Disease
Location: Santa Monica CA, Walnut Creek CA, Greenwood Village CO,
Sponsor: BioRestorative Therapies

Sex: All

Age: 18+

Code: NCT04042844

Phase 2, Recruiting
Active & Responsive

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

for
Phantom Limb Syndrome With Pain
Location: Santa Monica CA, Sacramento CA, San Anselmo CA,
Sponsor: The Ketamine Research Foundation

Sex: All

Age: 18 - 65

Code: NCT07276542

Phase 2, Phase 3, Recruiting
Active & Responsive

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

for
Treatment-resistant Schizophrenia
Location: Los Angeles CA, Baltimore MD, New York NY
Sponsor: Newron Pharmaceuticals SPA

Sex: All

Age: 18+

Code: NCT07184619

Phase 3, Recruiting

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Active & Responsive

Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor

for
Essential Tremor
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT07599592

Early Phase 1, Recruiting
Active & Responsive

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

for
Myotonic Dystrophy Type 1 (DM1), DM1, Myotonic Dystrophy,
Location: Los Angeles CA, La Jolla CA, Palo Alto CA,
Sponsor: Dyne Therapeutics

Sex: All

Age: 16+

Code: NCT07486934

Phase 3, Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Santa Monica CA, Los Angeles CA, Phoenix AZ,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase 1, Phase 2, Recruiting
Active & Responsive

Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

for
Solid Tumor Cancer
Location: Santa Monica CA
Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All

Age: 18+

Code: NCT07671534

Phase 2, Recruiting
Active & Responsive

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for
Alpha1-Antitrypsin Deficiency
Location: Los Angeles CA, La Jolla CA, Phoenix AZ, Palo Alto CA,
Sponsor: Takeda

Sex: All

Age: 18 - 70+

Code: NCT05677971

Phase 3, Recruiting
Active & Responsive

Study of DISC-0974-201 in Participants With IBD and Anemia

for
Inflammatory Bowel Disease (IBD), Anemia,
Location: Los Angeles CA, Scottsdale AZ, Kingwood TX,
Sponsor: Disc Medicine, Inc

Sex: All

Age: 18+

Code: NCT07368972

Phase 2, Recruiting
Active & Responsive

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Los Angeles CA, Stanford CA, Houston TX, Detroit MI,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07111520

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, Non-Small Cell Lung,
Location: Los Angeles CA, La Jolla CA, Gilbert AZ, Seattle WA,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06682793

Phase 1, Phase 2, Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: Santa Monica CA, La Jolla CA, Phoenix AZ, Gilbert AZ,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for
Solid Tumor, Adult, Colorectal Cancer, NSCLC,
Location: Los Angeles CA, La Jolla CA, Gilbert AZ, Stanford CA,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT06051695

Phase 1, Phase 2, Recruiting
Active & Responsive

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

for
Breast Cancer Screening, Artificial Intelligence (AI)
Location: Los Angeles CA, San Diego CA, Seattle WA, Madison WI,
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06934239

Recruiting
Active & Responsive

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

for
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF),
Location: Los Angeles CA, San Diego CA, Seattle WA, Milwaukee WI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 0+

Code: NCT05788536

Phase 1, Phase 2, Recruiting
Active & Responsive

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

for
Abdominal Injury, Pelvic Fracture, Genital Hemorrhage,
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 0+

Code: NCT04937868

Recruiting
Active & Responsive

Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication

for
Obesity & Overweight, Muscle Mass and Strength, Muscle Function
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT07806838

Recruiting
Active & Responsive

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

for
Depression in Adolescence
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 14 - 21

Code: NCT05329441

Recruiting