Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Hepatitis C Tracker Study
for
Hepatitis C Virus Infection
Location: Alhambra CA, Ventura CA
Sponsor: University of Southern California
Sex: All
Age: 18+
Code: NCT06870019
Recruiting
Family-based Intervention for Youth With Prader-Willi Syndrome: The Active Play at Home Study
for
Prader Willi Syndrome, Childhood Obesity
Location: Fullerton CA, Gainesville FL
Sponsor: California State University, Fullerton
Sex: All
Age: 8 - 15
Code: NCT02058342
Recruiting
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
for
Hypercholesterolemia
Location: Anaheim CA, Los Alamitos CA, Las Vegas NV,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18 - 70+
Code: NCT07477704
Phase2, Recruiting
A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants
for
Healthy Volunteers
Location: Anaheim CA, San Antonio TX, Lenexa KS
Sponsor: Karuna Therapeutics
Sex: All
Age: 18 - 65
Code: NCT07204418
Phase1, Recruiting
A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986521 in Healthy Participants.
for
Healthy Volunteers
Location: Anaheim CA
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18 - 70+
Code: NCT07283263
Phase1, Recruiting
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A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
for
Systemic Lupus Erythematosus (SLE),
Location: Los Angeles CA, Thousand Oaks CA, Allen TX,
Sponsor: EMD Serono Research & Development Institute, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07332481
Phase3, Recruiting
Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
for
Acute Myeloid Leukemia
Location: Los Angeles CA, San Francisco CA, Kansas City KS,
Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland
Sex: All
Age: 18+
Code: NCT07223814
Phase3, Recruiting
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
Location: Upland CA, Kelowna, Frisco TX, Humble TX,
Sponsor: EMD Serono Research & Development Institute, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07355218
Phase3, Recruiting
Study of Cannabidiol in Sanfilippo Syndrome
for
Sanfilippo Syndrome, Mucopolysaccharidosis III
Location: Torrance CA
Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Sex: All
Age: 4+
Code: NCT06333041
Phase2, Phase3, Recruiting
A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants.
for
Healthy
Location: Glendale CA
Sponsor: AstraZeneca
Sex: All
Age: 18 - 50
Code: NCT06995820
Phase1, Recruiting
Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer
for
Non Small Cell Lung Cancer
Location: Torrance CA, Monterey CA, Walnut Creek CA,
Sponsor: N-Power Medicine
Sex: All
Age: 18+
Code: NCT07028489
Recruiting
Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma
for
Safety in Asthma Patients
Location: Anaheim CA
Sponsor: Aspeya, Inc.
Sex: All
Age: 18 - 55
Code: NCT07665892
Phase1, Recruiting
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
for
Breast Cancer
Location: Fullerton CA, Los Angeles CA, Billings MT, Seattle WA,
Sponsor: Celcuity Inc
Sex: All
Age: 18+
Code: NCT06757634
Phase3, Recruiting
A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)
for
Healthy
Location: Anaheim CA
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18 - 55
Code: NCT07697625
Phase1, Recruiting
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease
for
Refractory Metastatic Colorectal Cancer
Location: Duarte CA, Santa Monica CA, Salt Lake City UT,
Sponsor: Delcath Systems Inc.
Sex: All
Age: 18+
Code: NCT06607458
Phase2, Recruiting
Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer
for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06860815
Phase2, Recruiting
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
for
Bipolar Depression
Location: Anaheim CA, West Covina CA, Redlands CA, San Diego CA,
Sponsor: Intra-Cellular Therapies, Inc.
Sex: All
Age: 10 - 17
Code: NCT06372964
Phase3, Recruiting
A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
for
COVID-19, SARS-CoV-2 Infection
Location: Los Angeles CA, San Francisco CA
Sponsor: Kara Chew
Sex: All
Age: 40 - 64
Code: NCT06810934
Phase1, Phase2, Recruiting
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
for
Prostate Cancer
Location: Los Angeles CA, Santa Monica CA, Santa Barbara CA,
Sponsor: Novartis Pharmaceuticals
Sex: Male
Age: 18 - 70+
Code: NCT06780670
Phase2, Phase3, Recruiting
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
for
Non-small Cell Lung Cancer
Location: Anaheim CA, Los Alamitos CA, Loma Linda CA,