Discover 3,562 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
for
Moderately to Severely Active Ulcerative Colitis
Location: Newport Beach CA, Garden Grove CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 16 - 70+
Code: NCT06588855
Phase3, Recruiting
FeaturedActive & Responsive
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for
Moderately to Severely Active Crohns Disease
Location: Garden Grove CA, Los Alamitos CA, Inglewood CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 16 - 70+
Code: NCT06819878
Phase3, Recruiting
FeaturedActive & Responsive
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
for
Metastatic Colorectal Cancer
Location: Duarte CA, Los Angeles CA, Phoenix AZ, Lone Tree CO,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT04929223
Phase1, Recruiting
FeaturedActive & Responsive
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251
for
Geographic Atrophy
Location: Beverly Hills CA, San Francisco CA, Sacramento CA,
Sponsor: Genentech, Inc.
Sex: All
Age: 50+
Code: NCT05626114
Phase2, Recruiting
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Featured
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
for
Alzheimers Disease
Location: Irvine CA, Santa Ana CA, Long Beach CA, Riverside CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 50 - 70+
Code: NCT07177352
Phase3, Recruiting
Featured
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
for
Alzheimers Disease
Location: Irvine CA, Santa Ana CA, Los Angeles CA, Sun City AZ,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 50 - 70+
Code: NCT07169578
Phase3, Recruiting
Featured
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
for
Atherosclerosis
Location: Irvine CA, Beverly Hills CA, West Hills CA, Redmond WA,
Sponsor: Genentech, Inc.
Sex: All
Age: 18 - 70+
Code: NCT07448038
Phase2, Recruiting
Featured
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
for
Neovascular Age-related Macular Degeneration
Location: Santa Ana CA, Huntington Beach CA, Torrance CA, Mesa AZ,
Sponsor: Genentech, Inc.
Sex: All
Age: 50+
Code: NCT04853251
Recruiting
Featured
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Irvine CA, Santa Monica CA, Duarte CA, Stanford CA,