Discover 3,420 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,420
FeaturedActive & Responsive
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
for
Bipolar Depression
Location: Anaheim CA, West Covina CA, Redlands CA, San Diego CA,
Sponsor: Intra-Cellular Therapies, Inc.
Sex: All
Age: 10 - 17
Code: NCT06372964
Phase3, Recruiting
Active & Responsive
Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
for
Breast Cancer Screening, Breast Carcinoma in Situ, Breast Cancer
Location: Irvine CA, Los Angeles CA, San Diego CA, San Francisco CA,
Sponsor: University of California, San Francisco
Sex: Female
Age: 30 - 70+
Code: NCT02620852
Recruiting
Active & Responsive
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
for
Prostate Cancer, Prostatic Neoplasms
Location: Irvine CA, Duarte CA, La Jolla CA, Billings MT,
Sponsor: Merck Sharp & Dohme LLC
Sex: Male
Age: 18+
Code: NCT06925737
Phase3, Recruiting
Active & Responsive
A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder
for
Depressive Disorder, Major
Location: Santa Ana CA, Orange CA, Newport Beach CA, Garden Grove CA,
Sponsor: Janssen Research & Development, LLC
Sex: All
Age: 18 - 64
Code: NCT06785012
Phase2, Recruiting
Active & Responsive
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
for
Obesity
Location: Santa Ana CA, Fountain Valley CA, Long Beach CA,
Sponsor: Amgen
Sex: All
Age: 18 - 70+
Code: NCT06858839
Phase3, Recruiting
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Active & Responsive
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
for
Advanced Liver Cancers
Location: Costa Mesa CA, Orange CA, Duarte CA, Santa Monica CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT04524871
Phase1, Phase2, Recruiting
Active & Responsive
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Location: Orange CA, Phoenix AZ, San Francisco CA, Dallas TX, Houston TX,
Sponsor: Carl Allen
Sex: All
Age: 0 - 70+
Code: NCT04079179
Phase2, Recruiting
Active & Responsive
Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder
for
Major Depressive Disorder
Location: Orange CA, Newport Beach CA, Garden Grove CA, Encino CA,
Sponsor: Neumora Therapeutics, Inc.
Sex: All
Age: 18 - 65
Code: NCT06058013
Phase3, Recruiting
Active & Responsive
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
for
Crohn's Disease
Location: Orange CA, Los Angeles CA, Murrieta CA, Las Vegas NV,
Sponsor: Takeda
Sex: All
Age: 18 - 70+
Code: NCT06233461
Phase2, Recruiting
Active & Responsive
A Trial of Centanafadine Efficacy and Safety in Adults With Attention-deficit/Hyperactivity Disorder and Comorbid Anxiety
for
ADHD, Anxiety, Generalized Anxiety, Social Anxiety Disorder
Location: Orange CA, Las Vegas NV, San Antonio TX, Memphis TN, Dothan AL,
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.