Discover 3,606 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,606
FeaturedActive & Responsive
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
for
Metastatic Breast Cancer
Location: Irvine CA, Duarte CA, Los Angeles CA, La Jolla CA,
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
for
Rheumatoid Arthritis
Location: Huntington Beach CA, Torrance CA, Upland CA,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT06972446
Phase 2, Recruiting
FeaturedActive & Responsive
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for
Moderately to Severely Active Crohns Disease
Location: Garden Grove CA, Los Alamitos CA, Inglewood CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 16 - 70+
Code: NCT06819878
Phase 3, Recruiting
FeaturedActive & Responsive
Type 2 Diabetes Studies on Blood Sugar and Weight Management for Adults Not on Insulin
for
Diabetes Mellitus, Type 2, Obesity
Location: Huntington Park CA, Gardena CA, San Bernardino CA,
Sex: All
Age: 18 - 70+
Recruiting
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Weight Loss Studies for Adults With a BMI of 27+, Including People Managing Type 2 Diabetes or Sleep Apnea
for
Obesity, Overweight, Diabetes Mellitus, Type 2,
Location: Huntington Park CA, Gardena CA, Oceanside CA,
Sex: All
Age: 18+
Recruiting
FeaturedActive & Responsive
Fatty Liver Disease (MASH/NASH) Studies for Adults Also Managing Diabetes, High Blood Pressure, or High Cholesterol
for
Non-alcoholic Fatty Liver Disease
Location: Huntington Park CA, Gardena CA, Los Angeles CA,
Sex: All
Age: 18 - 70+
Recruiting
FeaturedActive & Responsive
COVID-19 Study for People 12+ With a Current Infection Who Are at Higher Risk of Severe Illness
for
COVID-19
Location: Huntington Park CA, Grand Island NE, Omaha NE,
Sex: All
Age: 12+
Recruiting
Participants receive up to $259 for time and travel
FeaturedActive & Responsive
Cardiovascular Disease Studies for Adults With High Blood Pressure, High Cholesterol, AFib, or Heart Failure
Location: Huntington Park CA, Pasadena CA, San Bernardino CA,
Sex: All
Age: 18+
Recruiting
FeaturedActive & Responsive
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
for
Metastatic Colorectal Cancer
Location: Duarte CA, Los Angeles CA, Phoenix AZ, Lone Tree CO,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT04929223
Phase 1, Recruiting
FeaturedActive & Responsive
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251
for
Geographic Atrophy
Location: Beverly Hills CA, San Francisco CA, Sacramento CA,
Sponsor: Genentech, Inc.
Sex: All
Age: 50+
Code: NCT05626114
Phase 2, Recruiting
FeaturedActive & Responsive
Blood Sugar Management Studies for Adults With Type 1 Diabetes
for
Diabetes Mellitus, Type 1
Location: San Bernardino CA, Medford OR, Dallas TX
Location: San Bernardino CA, Peoria AZ, Phoenix AZ,
Sex: All
Age: 60+
Recruiting
FeaturedActive & Responsive
Gout Studies for Adults With Frequent Flares or Tophi
for
Gout
Location: San Bernardino CA, Waco TX, Norfolk NE, Columbus GA
Sex: All
Age: 18+
Recruiting
FeaturedActive & Responsive
Diabetic Nerve Pain Study of a Non-Opioid Medication for Adults With Ongoing Foot and Leg Pain
for
Diabetic Neuropathies
Location: San Bernardino CA, Albuquerque NM, Medford OR,
Sex: All
Age: 18 - 70+
Recruiting
FeaturedActive & Responsive
C. diff Vaccine Studies for Adults 65+ at Higher Risk of Infection
for
Clostridium Infections
Location: San Bernardino CA, Grand Island NE, Omaha NE,
Sex: All
Age: 65+
Recruiting
Participants receive up to $1,470 for time and travel
FeaturedActive & Responsive
Migraine Prevention Studies for Adults With 2–10 Moderate-to-Severe Attacks a Month
for
Migraine Disorders
Location: Van Nuys CA, Chula Vista CA, Phoenix AZ, Dallas TX,
Sex: All
Age: 18 - 70+
Recruiting
Featured
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
for
Alzheimer's Disease
Location: Irvine CA, Boulder CO, Dallas TX, Cordova TN,
Sponsor: AbbVie
Sex: All
Age: 50 - 70+
Code: NCT07599670
Phase 1, Phase 2, Recruiting
Featured
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
for
Alzheimers Disease
Location: Irvine CA, Santa Ana CA, Long Beach CA, Riverside CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 50 - 70+
Code: NCT07177352
Phase 3, Recruiting
Featured
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
for
Atherosclerosis
Location: Irvine CA, Beverly Hills CA, Los Angeles CA,