Paid Clinical Trials Irvine

Discover 2,478 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 2,478

LumateperoneMulticenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

Recruiting

PHASE3

Sponsor:

Intra-Cellular Therapies, Inc.

Location:

Anaheim CA, Bellflower CA, West Covina CA, Baldwin Park CAshow 38 more

Code:

NCT06372964

Conditions

Bipolar Depression

Eligibility Criteria

Sex: All

Age: 10 - 17

Healthy Volunteers: Not accepted

Interventions

Lumateperone

Placebo

Alisertib & Endocrine TherapyA Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Recruiting

PHASE2

Sponsor:

Puma Biotechnology, Inc.

Location:

Irvine CA, Los Angeles CA, Phoenix AZ, San Francisco CAshow 18 more

Code:

NCT06369285

Conditions

Hormone Receptor Positive HER-2 Negative Breast Cancer

Metastatic Breast Cancer

Recurrent Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Alisertib

Endocrine therapy

MK-1167A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)

Recruiting

PHASE2

Sponsor:

Merck Sharp & Dohme LLC

Location:

Irvine CA, Redlands CA, Sherman Oaks CA, Phoenix AZshow 27 more

Code:

NCT06721156

Conditions

Alzheimer Disease

Dementia

Eligibility Criteria

Sex: All

Age: 55 - 70+

Healthy Volunteers: Not accepted

Interventions

MK-1167

Placebo

Vepdegestrant & PF-07220060A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.

Recruiting

PHASE1

PHASE2

Sponsor:

Pfizer

Location:

Irvine CA, Newport Beach CA, Palo Alto CA, San Francisco CAshow 18 more

Code:

NCT06206837

Conditions

Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

vepdegestrant

PF-07220060

M3814 with RadiotherapyTesting the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Recruiting

PHASE1

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Irvine CA, Orange CA, Duarte CA, Sacramento CAshow 32 more

Code:

NCT04172532

Conditions

Locally Advanced Pancreatic Adenocarcinoma

Stage III Pancreatic Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy Procedure

Biospecimen Collection

Computed Tomography

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

[225Ac]-FPI-2068A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients with Advanced Solid Tumours

Recruiting

PHASE1

Sponsor:

Fusion Pharmaceuticals Inc.

Location:

Irvine CA, Santa Monica CA, Stanford CA, Seattle WAshow 11 more

Code:

NCT06147037

Conditions

Advanced Solid Tumor

Metastatic Colorectal Carcinoma

Head and Neck Squamous Cell Carcinoma

Non-small Cell Lung Cancer

Pancreatic Ductal Adenocarcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

FPI-2053

[111In]-FPI-2107

[225Ac]-FPI-2068

Observational StudyYouth Nominated Support Team

Recruiting

Sponsor:

UCLA

Location:

Irvine CA

Code:

NCT05558332

Conditions

Psychosis

Suicide

Health Care Utilization

Family Members

Eligibility Criteria

Sex: All

Age: 12 - 25

Healthy Volunteers: Not accepted

Interventions

Youth-Nominated Support Teams for CHR

PyLPyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Recruiting

PHASE2

Sponsor:

Hoag Memorial Hospital Presbyterian

Location:

Irvine CA

Code:

NCT04700332

Conditions

Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

DCFPyL PET/CT

ImmunoPETA Diagnostic Study of CD38-Targeted ImmunoPET of Myeloma

Recruiting

PHASE2

Sponsor:

Hoag Memorial Hospital Presbyterian

Location:

Irvine CA, Miami FL

Code:

NCT04814615

Conditions

Multiple Myeloma

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Interventions

89Zr-daratumumab PET/CT

Positive Affect TreatmentPositive Affect Treatment for Adolescents with Early Life Adversity

Recruiting

Sponsor:

UCLA

Location:

Irvine CA

Code:

NCT06273137

Conditions

Depression

Eligibility Criteria

Sex: All

Age: 12 - 16

Healthy Volunteers: Accepted

Interventions

Positive affect treatment

Supportive psychotherapy (SUP)