Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
New
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
for
Obesity
Location: Lake Forest CA
Sponsor: Pfizer
Sex: All
Age: 18 - 70
Code: NCT07731139
Phase1, Recruiting
New
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
for
Overweight, Prediabetic State, Prehypertension,
Location: Lake Forest CA, Long Beach CA, Riverside CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07794579
Phase3, Recruiting
CTSN Embolic Protection Trial
for
Delirium, Ischemic Stroke, Acute Kidney Injury,
Location: Los Angeles CA, Kansas City MO, North Little Rock AR,
Sponsor: Icahn School of Medicine at Mount Sinai
Sex: All
Age: 60+
Code: NCT06027788
Recruiting
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
for
Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma,
Location: Fullerton CA, Tacoma WA, Spokane WA, Tyler TX,
Sponsor: Panbela Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05254171
Phase2, Phase3, Recruiting
A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)
for
Acute Myeloid Leukemia, in Relapse,
Location: Los Angeles CA, La Jolla CA, Houston TX, New York NY
Sponsor: Bio-Path Holdings, Inc.
Sex: All
Age: 18+
Code: NCT05190471
Phase1, Recruiting
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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
for
Rheumatic Joint Disease
Location: Los Angeles CA, San Diego CA, Phoenix AZ, Palo Alto CA,
Sponsor: Duke University
Sex: All
Age: 0 - 21
Code: NCT02418442
Recruiting
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
for
Acute Myeloid Leukemia,
Location: Los Angeles CA, Las Vegas NV, Phoenix AZ,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18 - 59
Code: NCT05554406
Phase2, Recruiting
A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.
for
Severe Hemophilia A
Location: Los Angeles CA, Greenville NC
Sponsor: Pfizer
Sex: Male
Age: 12 - 70+
Code: NCT06703606
Phase1, Recruiting
A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
for
Parkinson Disease
Location: Irvine CA, Loma Linda CA, Las Vegas NV,
Sponsor: AskBio Inc
Sex: All
Age: 45 - 70+
Code: NCT06285643
Phase2, Recruiting
Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors
for
Muscle-Invasive Bladder Carcinoma,
Location: Santa Monica CA
Sponsor: Vasgene Therapeutics, Inc
Sex: All
Age: 18+
Code: NCT06493552
Phase2, Phase3, Recruiting
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
for
Primary Generalized Tonic-Clonic Seizures
Location: Orange CA, Los Angeles CA, Phoenix AZ, Tucson AZ,
Sponsor: Xenon Pharmaceuticals Inc.
Sex: All
Age: 12+
Code: NCT05667142
Phase3, Recruiting
Exercise for Brain Regeneration in Epilepsy
for
Temporal Lobe Epilepsy
Location: Los Angeles CA
Sponsor: University of Southern California
Sex: All
Age: 18 - 65
Code: NCT05179083
Phase1, Recruiting
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
for
Cytokine Release Syndrome
Location: Orange CA, Seattle WA, Augusta GA, Pittsburgh PA,
Sponsor: CytoAgents, Inc.
Sex: All
Age: 18+
Code: NCT05905328
Phase1, Phase2, Recruiting
Starting Technology in At Risk Type 1 Diabetes Study
for
Diabetes Mellitus, Type 1
Location: Torrance CA, Santa Monica CA, Sylmar CA
Sponsor: University of California, Los Angeles
Sex: All
Age: 18+
Code: NCT06453928
Recruiting
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
for
Ulcerative Colitis, Crohn's Disease
Location: Murrieta CA, Escondido CA, Sun City AZ, Kingwood TX,
Sponsor: Takeda
Sex: All
Age: 18 - 70+
Code: NCT06581328
Recruiting
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
for
Pulmonary Embolism
Location: Orange CA, Long Beach CA, Los Angeles CA, San Diego CA,
Sponsor: Penumbra Inc.
Sex: All
Age: 18+
Code: NCT04798261
Recruiting
Sensory Motor Transformations in Human Cortex
for
Quadriplegia
Location: Downey CA, Los Angeles CA, Pasadena CA, Aurora CO
Sponsor: Richard A. Andersen, PhD
Sex: All
Age: 22 - 65
Code: NCT01964261
Recruiting
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
for
Hormone-refractory Prostate Cancer
Location: Orange CA, Palo Alto CA, Seattle WA, Houston TX,
Sponsor: Astellas Pharma Global Development, Inc.
Sex: Male
Age: 18+
Code: NCT05997615
Phase1, Recruiting
ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies